A Common Variant of ASAP1 Is Associated with Tuberculosis Susceptibility in the Han Chinese Population

Table 2

The genotype distribution of rs4733781 among tuberculosis cases and controls.

SNP rs4733781	Cases; (%)	Controls; (%)	OR (95% CI)		IGRA-positive controls; (%)	OR (95% CI)		IGRA-negative controls; (%)	OR (95% CI)
	954	951			215			736
CC	361 (37.8)	304 (32.0)	1.00 (reference)		78 (36.3)	1.00 (reference)		226 (30.7)	1.00 (reference)
CA	461 (48.3)	483 (50.8)	0.81 (0.66-0.99)	0.0373	102 (47.4)	0.98 (0.71-1.35)	0.8881	381 (51.8)	0.76 (0.61-0.95)	0.0159
AA	132 (13.8)	164 (17.2)	0.68 (0.51-0.89)	0.0059	35 (16.2)	0.82 (0.52-1.28)	0.382	129 (17.5)	0.64 (0.47-0.89)	0.0034
CA+AA	593 (62.2)	647 (68.0)	0.78 (0.64-0.94)	0.0086	137 (63.7)	0.94 (0.69-1.28)	0.677	510 (69.3)	0.73 (0.60-0.90)	0.0033
MAF	0.38	0.43
HWE		0.24

Adjusted by age and gender. HWE: Hardy-Weinberg equilibrium; IGRA: interferon-gamma release assay.