Associations between TAB2 Gene Polymorphisms and Epithelial Ovarian Cancer in a Chinese Population

Table 2

Genotype and allele distribution of TAB2 gene polymorphisms in patients with epithelial ovarian cancer and healthy controls.

Genotype or allele		Case; (%)	Control; (%)	OR (95% CI)	value
rs237028; Genetic model	Genotype
Codominant	A/A	144 (66.4)	137 (54.4)	1.00	0.03
	A/G	61 (28.1)	97 (38.5)	1.67 (1.12-2.49)
	G/G	12 (5.5)	18 (7.1)	1.58 (0.73-3.39)
Dominant	A/A	144 (66.4)	137 (54.4)	1.00	0.008
	A/G-G/G	73 (33.6)	115 (45.6)	1.66 (1.14-2.41)
Recessive	A/A-A/G	205 (94.5)	234 (92.9)	1.00	0.47
	G/G	12 (5.5)	18 (7.1)	1.31 (0.62-2.79)
Overdominant	A/A-G/G	156 (71.9)	155 (61.5)	1.00	0.017
	A/G	61 (28.1)	97 (38.5)	1.60 (1.08-2.36)
Allele	A	349 (80)	371 (74)		0.016
	G	85 (20)	133 (26)	1.45 (1.07-1.96)
rs521845; Genetic model
Codominant	T/T	85 (40.5)	105 (41.7)	1.00	0.97
	T/G	100 (47.6)	118 (46.8)	0.96 (0.65-1.41)
	G/G	25 (11.9)	29 (11.5)	0.94 (0.51-1.72)
Dominant	T/T	85 (40.5)	105 (41.7)	1.00	0.80
	T/G-G/G	125 (59.5)	147 (58.3)	0.95 (0.66-1.38)
Recessive	T/T-T/G	185 (88.1)	223 (88.5)	1.00	0.89
	G/G	25 (11.9)	29 (11.5)	0.96 (0.54-1.70)
Overdominant	T/T-G/G	110 (52.4)	134 (53.2)	1.00	0.86
	T/G	100 (47.6)	118 (46.8)	0.97 (0.67-1.40)
Allele	T	270 (64)	328 (65)	0.96 (0.73-1.27)	0.8
	G	150 (36)	176 (35)
rs652921; Genetic model
Codominant	T/T	66 (32.5)	85 (33.7)	1.00	0.53
	T/C	87 (42.9)	116 (46)	1.04 (0.68-1.58)
	C/C	50 (24.6)	51 (20.2)	0.79 (0.48-1.31)
Dominant	T/T	66 (32.5)	85 (33.7)	1.00	0.78
	T/C-C/C	137 (67.5)	167 (66.3)	0.95 (0.64-1.40)
Recessive	T/T-T/C	153 (75.4)	201 (79.8)	1.00	0.26
	C/C	50 (24.6)	51 (20.2)	0.78 (0.50-1.21)
Overdominant	T/T-C/C	116 (57.1)	136 (54)	1.00	0.5
	T/T	87 (42.9)	116 (46)	1.14 (0.78-1.65)
Allele	T	219 (54)	286 (57)	0.90 (0.70-1.16)	0.42
	C	187 (46)	218 (43)

CI = confidence interval, OR = odds ratio. .