High Lipoprotein(a) Level Is Independently Associated with Adverse Clinicopathological Features in Patients with Prostate Cancer

Table 4

Univariate and multivariate analyses to identify the independent correlation between high Lp(a) and high risk of PCa.

	Univariate model		Multivariate model
	OR (95% CI)	value	OR (95% CI)	value
TG (mmol/l)	1.154 (0.700-1.902)	0.575
TC (mmol/l)	0.931 (0.694-1.249)	0.633
LDL-C (mmol/l)	0.839 (0.578-1.220)	0.358
HDL-C (mmol/l)	1.196 (0.460-3.110)	0.714
TC/HDL-C	0.818 (0.596-1.122)	0.213
LDL-C/HDL-C	0.738 (0.493-1.106)	0.141
RC (mmol/l)	1.054 (0.451-2.465)	0.903
Lp(a) (mg/l)
Quartile 1	1		1
Quartile 2	1.864 (0.833-4.170)	0.130	1.957 (0.862-4.442)	0.109
Quartile 3	1.219 (0.584-2.545)	0.598	1.239 (0.581-2.641)	0.579
Quartile 4	2.687 (1.113-6.491)	0.028	2.890 (1.148-7.274)	0.024

Logistic regression analyses were performed. The multivariate model was adjusted for age, BMI, hypertension, diabetes, coronary artery disease, and lipid-lowering drugs. The bold value indicated statistical significance. PCa = prostate cancer; RC = remnant cholesterol; TC = total cholesterol; HDL-C = high-density lipoprotein cholesterol; LDL-C = low-density lipoprotein cholesterol; TG = triglycerides; Lp(a) = lipoprotein(a).