Associations of IDUA and PTCH1 with Bone Mineral Density, Bone Turnover Markers, and Fractures in Chinese Elderly Patients with Osteoporosis

Table 4

Associations of SNPs genotyped with BTMs and BMDs in participants with osteoporotic fractures.

Variable	rs3755955				rs6831280				rs28377268
	CC	CT	TT		GG	GA	AA		AA	AC	CC
β-CTX (ng/ml)	83			0.418				0.387				0.438
PINP (ng/ml)				0.312				0.215				0.551
BMD-L2-4 (g/cm^2)				0.695				0.136				0.499
BMD-FN (g/cm^2)				0.722				0.307				0.418
BMD-WT (g/cm^2)				0.767				0.543				0.601
BMD-FT (g/cm^2)				0.767				0.747				0.636
BMD-TH (g/cm^2)				0.545				0.513				0.728

β-CTX: procollagen type I carboxy terminal peptide beta special sequence; PINP: procollagen I N-terminal propeptide; BMD: bone mineral density; L2-4: L2-4 vertebra; FN: femoral neck; WT: Ward’s triangle; FT: femoral trochanter; TH: total hip. All values were adjusted for age and BMI by ANCOVA.