Disease Markers

Research Article

Haplotypes of HTRA1 rs1120638, TIMP3 rs9621532, VEGFA rs833068, CFI rs10033900, ERCC6 rs3793784, and KCTD10 rs56209061 Gene Polymorphisms in Age-Related Macular Degeneration

Table 4

Binomial logistic regression analysis of the CFI rs10033900, ERCC6 rs3793784, VEGFA rs833068, HTRA1 rs11200638, TIMP3 rs9621532, and KCTD10 rs56209061 SNPs in early AMD and control groups.


Early AMD
SNP	Model/genotype/allele	OR; 95% CI;	AIC

	Codominant
rs56209061	GA vs. GG	0.471; 0.307-0.724; 0.001	842.895
rs56209061	AA vs. GG	0.343; 0.066-1.786; 0.204	842.895

	Dominant
rs56209061	GA+AA vs. GG	0.463; 0.305-0.704; <0.001	841.036

	Recessive
rs3793784	CC vs. GC+GG	2.007; 1.255-3.209; 0.004	845.769

	Overdominant
rs56209061	GA vs. GG+AA	0.478; 0.312-0.733; 0.001	842.698

	Additive
rs11200638	A	1.387; 1.096-1.755; 0.007	847.056
rs56209061	A	0.491; 0.332-0.726; <0.001	841.104

OR: odds ratio; 95% CI: 95% confidence interval; values < 0.008 indicated in bold are statistically significant; AIC: Akaike information criterion.