Disease Markers / 2019 / Article / Tab 2

Research Article

Association between the -844 G>A, HindIII C>G, and 4G/5G PAI-1 Polymorphisms and Susceptibility to Multiple Sclerosis in Western Mexican Population

Table 2

Allele and genotype distributions of -844 G>A, HindIII C>G, and 4G/5G PAI-1 polymorphisms in MS and CS.

PolymorphismMS % ()CS % ()OR (CI 95%);

-844 G>A
 Genotype
  GG40 (80)45.5 (91)1
  GA52.5 (105)44.5 (89)1.3 (0.88-2.02); 0.16
  AA7.5 (15)10 (20)0.8 (0.41-1.77); 0.67
 Allele
  G33.8 (135)67.8 (271)1
  A66.2 (265)32.2 (129)1.1 (0.79-1.43); 0.65
HindIII C>G
 Genotype
  CC44 (88)50.5 (101)1
  CG47 (94)34 (68)1.58 (1.04-2.42); 0.03
  GG9 (18)10.5 (21)0.98 (0.49-1.964); 0.96
 Allele
  G32.5 (130)30 (120)1.12 (0.833-1.515); 0.44
  C67.5 (270)70 (280)1
4G/5G
 Genotype
  4G/4G45.5 (91)44.5 (89)1.18 (0.79-1.79); 0.40
  4G/5G43 (86)50 (100)1
  5G/5G11.5 (23)5.5 (11)2.43 (1.12-5.27); 0.02
 Allele
  4G67 (268)69.5 (278)1
  5G33 (132)30.5 (122)1.36 (1.01-1.83); 0.04

MS: multiple sclerosis; CS: control subjects; OR: odds ratio; CI: confidence interval. .

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