Disease Markers / 2019 / Article / Tab 2 / Research Article
Proximal Gastrectomy versus Total Gastrectomy for Siewert Type II Adenocarcinoma of the Esophagogastric Junction: A Comprehensive Analysis of Data from the SEER Registry Table 2 Univariate and multivariate analyses for 1,254 AEG patients.
Characteristics Univariate analysis Multivariate analysis HR [95% CI] HR [95% CI] Age <65 years 1 <0.01 1 <0.01 ≥65 years 1.509 [1.296-1.758] 1.650 [1.412-1.928] Marital status Married 1 0.001 1 0.003 Others 1.329 [1.126-1.568] 1.292 [1.093-1.527] Grade Well/moderately 1 <0.01 1 0.017 Poorly/undifferentiated 1.486 [1.267-1.743] 1.220 [1.036-1.436] AJCC stage Stage IA 1 <0.01 1 <0.01 Stage IB 2.391 [1.738-3.288] <0.01 2.121 [1.528-2.942] <0.01 Stage II 3.146 [2.349-4.212] <0.01 2.318 [1.576-3.408] <0.01 Stage IIIA 3.716 [2.734-5.051] <0.01 2.283 [1.467-3.555] <0.01 Stage IIIB 3.706 [2.428-5.655] <0.01 1.837 [1.022-3.302] 0.042 AJCC N stage N0 1 <0.01 1 <0.01 N1 2.022 [1.690-2.419] <0.01 1.447 [1.096-1.911] 0.009 N2 2.601 [2.067-3.274] <0.01 2.429 [1.620-3.641] <0.01 Surgery Proximal gastrectomy 1 0.139 1 0.012 Total gastrectomy 1.121 [0.963-1.305] 1.216 [1.043-1.418] Regional lymph nodes examined 1-10 nodes 1 <0.01 1 <0.01 11-20 nodes 0.743 [0.624-0.884] 0.001 0.635 [0.532-0.759] <0.01 >20 nodes 0.651 [0.533-0.794] <0.01 0.530 [0.431-0.651] <0.01 Year 2004-2009 1 0.020 — 0.266 2010-2014 0.815 [0.687-0.968] — AJCC T stage T1 1 <0.01 — 0.963 T2 2.285 [1.814-2.879] <0.01 — 0.963 T3 2.213 [1.699-2.881] <0.01 — 0.963 Tumor size (mm) 1-20 1 <0.01 — 0.289 21-50 1.713 [1.341-2.188] <0.01 — 0.679 >50 2.171 [1.684-2.800] <0.01 — 0.205 Gender Male 1 0.726 Female 0.815 [0.687-0.968] Race White 1 0.464 Black 1.021 [0.751-1.388] 0.896 Others 0.858 [0.670-1.098] 0.224 Chemotherapy No/unknown 1 0.632 Yes 0.963 [0.823-1.125] Radiation None/unknown 1 0.584 Beam radiation 0.958 [0.823-1.116] Neoadjuvant radiation None/unknown 1 0.875 Yes 0.989 [0.862-1.135]