| | Gene/SNP | Major allele | Minor allele | MAF | Reported GWAS value | Nominal value in Pakistanis | OR (95% CI) | FDR () |
| | LINC00824/rs1516971 | T | C | 0.099 | 3.20E-11 | 4.73E-06 | 0.57 (0.45, 0.73) | 2.37E-04 | | PADI4/rs2240336 | C | T | 0.452 | 5.9E−9 | 5.00E-05 | 0.74 (0.64, 0.86) | 1.25E-03 | | CEP57/rs4409785 | T | C | 0.262 | 3.60E-09 | 1.03E-03 | 1.33 (1.12, 1.58) | 1.54E-02 | | CTLA4/rs3087243 | A | G | 0.422 | 1.2E−8 | 1.23E-03 | 1.28 (1.1, 1.49) | 1.54E-02 | | STAT4/rs13426947 | G | A | 0.238 | 7.2E−10 | 2.59E-03 | 1.31 (1.1, 1.56) | 2.59E-02 | | HLA-B/MICA/rs2596565 | G | A | 0.119 | 9.26E-09 | 4.53E-03 | 1.4 (1.11, 1.77) | 3.77E-02 | | C5orf30/rs26232 | C | T | 0.181 | 4.10E-08 | 3.73E-02 | 0.83 (0.69, 0.99) | 1.52E-01 | | CCL21/rs951005 | A | G | 0.248 | 3.90E-10 | 2.75E-02 | 0.82 (0.69, 0.98) | 1.52E-01 | | GATA3/rs2275806 | A | G | 0.397 | 4.6E−8 | 4.02E-02 | 1.17 (1.01, 1.36) | 1.52E-01 | | VPS37C/rs595158 | A | C | 0.320 | 3.4E−8 | 3.10E-02 | 1.19 (1.02, 1.38) | 1.52E-01 | | HLA-DRB1/rs660895 | A | G | 0.111 | <1E-300 | 4.02E-02 | 1.27 (1.01, 1.59) | 1.52E-01 | | EOMES/rs3806624 | G | A | 0.262 | 2.80E-08 | 3.54E-02 | 0.84 (0.71, 0.99) | 1.52E-01 | | SPRED2/rs934734 | A | G | 0.406 | 5.30E-10 | 4.24E-02 | 1.17 (1.01, 1.35) | 1.52E-01 | | RUNX1/rs9979383 | T | C | 0.300 | 5.0E−10 | 3.48E-02 | 0.84 (0.72, 0.99) | 1.52E-01 | | IL2RA/rs706778 | T | C | 0.458 | 1.40E-11 | 6.21E-02 | 0.87 (0.75, 1.01) | 2.07E-01 | | LOC105378654/rs883220 | C | A | 0.212 | 2.1E−8 | 1.08E-01 | 0.87 (0.73, 1.03) | 3.17E-01 | | IRF5/rs10488631 | T | C | 0.196 | 4.20E-11 | 1.07E-01 | 1.16 (0.97, 1.39) | 3.17E-01 | | RCAN1/rs2834512 | G | A | 0.160 | 2.1E−8 | 1.39E-01 | 0.86 (0.71, 1.05) | 3.86E-01 | | ARID5B/rs12764378 | G | A | 0.241 | 4.5E−10 | 1.64E-01 | 1.13 (0.95, 1.34) | 4.33E-01 | | TYK2/rs34536443 | G | C | 0.010 | 2.3E−14 | 1.73E-01 | 0.62 (0.31, 1.23) | 4.33E-01 | | IL6R/rs2228145 | A | C | 0.323 | 1.3E−8 | 1.89E-01 | 0.9 (0.77, 1.05) | 4.50E-01 | | PTPN22/rs2476601 | G | A | 0.016 | 7.5E−77 | 2.21E-01 | 1.47 (0.79, 2.73) | 4.93E-01 | | SYNGR1/rs909685 | T | A | 0.480 | 6.40E-12 | 2.27E-01 | 1.09 (0.95, 1.26) | 4.93E-01 | | MTF1/rs28411352 | C | T | 0.222 | 5.90E-09 | 2.42E-01 | 1.11 (0.93, 1.32) | 5.05E-01 | | CCR6/rs3093023 | G | A | 0.425 | 1.50E-11 | 2.70E-01 | 1.09 (0.94, 1.26) | 5.19E-01 | | ALS2CR12/rs6715284 | C | G | 0.185 | 2.50E-09 | 2.61E-01 | 1.11 (0.92, 1.35) | 5.19E-01 | | UBASH3A/rs1893592 | A | C | 0.241 | 9.80E-09 | 3.11E-01 | 0.92 (0.77, 1.08) | 5.75E-01 | | IRF8/rs13330176 | T | A | 0.243 | 4.0E−8 | 4.04E-01 | 0.93 (0.78, 1.11) | 6.13E-01 | | PLCL2/rs4452313 | A | T | 0.492 | 5.2E-11 | 3.76E-01 | 1.07 (0.92, 1.24) | 6.13E-01 | | ACOXL/rs6732565 | G | A | 0.444 | 9.40E-09 | 4.15E-01 | 0.94 (0.81, 1.09) | 6.13E-01 | | GRHL2/rs678347 | A | G | 0.425 | 7.30E-10 | 4.17E-01 | 1.06 (0.92, 1.23) | 6.13E-01 | | TLE3/rs8026898 | G | A | 0.303 | 9.16.E-14 | 3.50E-01 | 0.93 (0.79, 1.09) | 6.13E-01 | | RASGRP1/rs8043085 | G | T | 0.280 | 1.4E−10 | 3.64E-01 | 1.08 (0.92, 1.27) | 6.13E-01 | | REL/rs34695944 | T | C | 0.112 | 1.4E−10 | 4.05E-01 | 1.1 (0.88, 1.39) | 6.13E-01 | | COG6/rs9603616 | C | T | 0.260 | 2.80E-11 | 4.47E-01 | 0.94 (0.8, 1.11) | 6.38E-01 | | TPD52/rs998731 | T | C | 0.434 | 6.60E-09 | 5.04E-01 | 0.95 (0.82, 1.1) | 7.00E-01 | | TNFAIP3/rs6920220 | G | A | 0.132 | 2.3E−13 | 5.33E-01 | 1.07 (0.86, 1.34) | 7.20E-01 | | CD40/rs4810485 | G | T | 0.250 | 2.8E−9 | 6.03E-01 | 0.96 (0.81, 1.13) | 7.94E-01 | | RAD51B/rs1950897 | T | C | 0.208 | 5.00E-08 | 7.02E-01 | 1.04 (0.86, 1.24) | 8.98E-01 | | FAM107A/rs13315591 | T | C | 0.043 | 4.60E-08 | 7.25E-01 | 1.06 (0.75, 1.51) | 8.98E-01 | | MMEL1/rs2843401 | C | T | 0.461 | 6.6E−9 | 7.80E-01 | 1.02 (0.88, 1.18) | 8.98E-01 | | RBPJ/rs874040 | G | C | 0.159 | 1.00E-16 | 8.20E-01 | 0.98 (0.81, 1.18) | 8.98E-01 | | IKZF3/rs12936409 | C | T | 0.392 | 2.8E−9 | 8.19E-01 | 0.98 (0.85, 1.14) | 8.98E-01 | | LBH/rs10175798 | A | G | 0.474 | 4.20E-08 | 8.46E-01 | 1.01 (0.88, 1.17) | 8.98E-01 | | LINC02356/rs10774624 | A | G | 0.138 | 6.90E-09 | 8.38E-01 | 0.98 (0.79, 1.2) | 8.98E-01 | | FADS2/rs968567 | G | A | 0.084 | 1.80E-08 | 8.62E-01 | 0.98 (0.75, 1.27) | 8.98E-01 | | AFF3/rs11676922 | T | A | 0.485 | 1.00E-14 | 7.91E-01 | 0.98 (0.85, 1.14) | 8.98E-01 | | CDK6/rs4272 | A | G | 0.083 | 1.2E-8 | 7.64E-01 | 0.96 (0.74, 1.24) | 8.98E-01 | | TEC/rs2664035 | G | A | 0.256 | 3.30E-08 | 9.54E-01 | 1 (0.84, 1.17) | 9.70E-01 | | TXNDC11/rs4780401 | T | G | 0.430 | 8.70E-09 | 9.70E-01 | 1 (0.86, 1.16) | 9.70E-01 |
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