Upregulation of FEN1 Is Associated with the Tumor Progression and Prognosis of Hepatocellular Carcinoma

Figure 4

Analysis of the relationships between FEN1 expression and prognosis in HCC TCGA samples. (a) Kaplan-Meier overall survival analysis between different degrees of FEN1 expression. (b) Kaplan-Meier relapse-free survival analysis between different degrees of FEN1 expression. (c, d) Kaplan-Meier overall survival analysis between different degrees of FEN1 and different degrees of the TNM stage. (e–h) The gene set enrichment analysis from TCGA HCC dataset revealed a high expression of FEN1 correlated with gene signatures of poor survival. FEN1: flap endonuclease 1; HCC: hepatocellular carcinoma; GEO: Gene Expression Omnibus; TCGA: The Cancer Genome Atlas; NES: not otherwise specified.

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