Research Article
Plasma-Derived Exosomal Circular RNA hsa_circ_0005540 as a Novel Diagnostic Biomarker for Coronary Artery Disease
Table 1
Characteristics of the study populations.
| | Characteristics | Profiling phase | Internal validation phase | External validation phase | | Non-CAD () | CAD () | Non-CAD () | CAD () | Non-CAD () | CAD () |
| | Age (years) | | | | | | | | Sex (male) | 2 (66.67%) | 1 (33.33%) | 13 (37.14%) | 36 (62.06%) | 19 (37.25%) | 35 (74.47%) | | Smoking | 0 (0%) | 1 (33.33%) | 5 (14.28%) | 26 (44.83%) | 0 (0%) | 8 (17.02%) | | Hypertension | 1 (33.33%) | 3 (100.00%) | 12 (34.29%) | 37 (63.79%) | 9 (17.65%) | 16 (34.04%) | | Diabetes | 0 (0%) | 2 (66.67%) | 1 (2.86%) | 18 (31.03%) | 5 (9.80%) | 16 (34.04%) | | Systolic BP (mmHg) | | | | | | | | FPG (mM) | | | | | | | | TC (mM) | | | | | | | | HDL (mM) | | | | | | | | Coronary artery disease | | | | | | | | 1 vessel | | 1 (33.33%) | | 25 (43.10%) | | 17 (36.17%) | | 2 vessels | | 1 (33.33%) | | 24 (41.38%) | | 19 (40.43%) | | 3 vessels | | 1 (33.33%) | | 9 (15.52%) | | 11 (23.40%) |
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Data are summarized by either . Abbreviations: BP: blood pressure; FPG: fasting plasma glucose; TC: total cholesterol; HDL: high-density lipoprotein. |
