Research Article

Use of the Nuclear Matrix Protein 22 BladderChek Test for the Detection of Primary and Recurrent Urothelial Carcinoma

Table 5

Comparison of diagnostic performance among the NMP22 BladderChek test, urine cytology, and the combination of two tests for the diagnosis of primary urothelial carcinoma based on clinical diagnosis.

Number of patientsCytologyNMP22 value
AgreementDisagreementAgreementDisagreement

NMP220.017
Agreement505
Disagreement1718
Combination1.000#; 0.001&
Agreement6155511
Disagreement618024

Note: the McNemar test was performed to compare the diagnostic values among the NMP22 BladderChek test, urine cytology, and the combination of two tests; NMP22 vs. cytology; #combination vs. cytology; &combination vs. NMP22.