CD26-Related Serum Biomarkers: sCD26 Protein, DPP4 Activity, and Anti-CD26 Isotype Levels in a Colorectal Cancer-Screening Context

Table 2

Levels of serum DPP-IV activity, sCD26 concentration, and anti-CD26/DPP-IV autoantibody isotypes according to demographic characteristics and origin of the cohort.

Characteristic	DPP4; (mU/mL)			sCD26; (ng/mL)			IgA; (Abs450nm)			IgG; (Abs450nm)			IgM; (Abs450nm)
			value			value			value			value			value
Sex
Men	182		0.002^a	189		0.176^a	76		0.530^a	76		0.328^a	76		0.146^a
Women	146			144			48			49			49
Age (years)
≤50	126			126			54			55			55
51-60	95		0.206^b	94		0.494^b	40		0.062^b	40		0.716^b	40		0.296^b
≥61	50			51			29			29			29
Group
CTG ()	50		0.542^a	50		0.528^a	25		0.863^a	25		0.673^a	25		0.005^a
HCU ()	434			443			112			113			113
HCU group relative to FIT
Negative for FIT ()	137		0.249^a	135		0.652^a	22		0.535^a	23		0.851^a	23		0.842^a
Positive for FIT ()	84			86			77			77			77

FIT: faecal immunochemical test; ^aStudent’s test; ^bANOVA test.