Disease Markers

Research Article

Plasma Homocysteine and Autonomic Nervous Dysfunction: Association and Clinical Relevance in OSAS

Table 2

OSAS and HRV characteristics stratified by Hcy quartiles.


Variables	Hcy quartiles (μmol/L)
Variables	Q1 (<11.3)	Q2 (11.3-14.3)	Q3 (14.4-18.3)	Q4 (>18.3)	for trend

Severe/total	13/50	15/47	18/47	25/47
OSAS, (%)	(26%)	(31.9%)	(38.3%)	(53.2%)	0.04/0.01
SDANN					0.14/0.02
SDNN					0.26/0.07
pNN50	7 (3, 15)	8 (5, 16)	8 (2, 14)	5 (3, 10)	0.45/0.43
EF (%)					0.83/0.91
ratio					0.18/0.64
LVEDD (mm)					0.64/0.41

Categorical values were compared by the test. Analysis of variance (ANOVA) or Wilcoxon’s rank sum test for continuous values. SDNN: standard deviation of normal-to-normal intervals; SDANN: standard deviation of the averages of normal-to-normal intervals in all 5 min segments; pNN50: NN50 count divided by the total number of all normal-to-normal intervals.