Comparative Proteomic Investigation of Plasma Reveals Novel Potential Biomarker Groups for Acute Aortic Dissection

Table 1

Clinical features of subjects used for iTRAQ and ELISA analysis.

iTRAQ	AAD	Control	value
	20	20	—
Age (mean (± SD))			0.105^a
Female ( (%))	4 (20.0)	6 (30.0)	0.465^b
Male ( (%))	16 (80.0)	14 (70.0)	0.465^b
Stanford type A	0	—	—
Stanford type B	18	—	—
Intramural hematoma	2	—	—
Hypertension ( (%))	15 (75.0)	8 (40.0)	0.025^b
Diabetes mellitus ( (%))	1	0	—
Smoking ( (%))	14 (70.0)	7 (35.0)	0.027^b
TC (mean (± SD))			0.130^a
LDL-C (mean (± SD))			0.533^a
HDL-C (mean (± SD))			0.556^a
TG (mean (± SD))			0.375^a
ELISA	AAD	Control	value
	60	50	—
Age (mean (± SD))			0.317^a
Female ( (%))	10 (16.7)	8 (16.0)	0.925^b
Male ( (%))	50 (83.3)	42 (84.0)	0.925^b
Stanford type A	5	—	—
Stanford type B	45	—	—
Intramural hematoma	10	—	—
Hypertension ( (%))	46 (76.7)	24 (48.0)	0.002^b
Diabetes mellitus ( (%))	3 (5.0)	0	—
Smoking ( (%))	32 (53.3)	26 (52.0)	0.889^b
TC (mean (± SD))			0.010^a
LDL-C (mean (± SD))			0.079^a
HDL-C (mean (± SD))			0.010^a
TG (25%–75% percentiles)	0.82~1.89	0.89~1.93	0.588^c

^a-test. ^bChi-square test. ^cMann-Whitney test. TC: total cholesterol; LDL-C: low-density lipoprotein-cholesterol; HDL-C: high-density lipoprotein cholesterol; TG: triglyceride.