Research Article
Overexpression of Spondin-2 Is Associated with Recurrence-Free Survival in Patients with Localized Clear Cell Renal Cell Carcinoma
Table 3
Uni- and multivariate analyses for predicting recurrence-free survival rate of patients with localized ccRCC.
| Characteristics | Univariate analysis | Multivariate analysis | Hazard ratio (95% confidence interval) | value | Hazard ratio (95% confidence interval) | value |
| Age (<60 vs. ≥60) | 3.817 (0.986-14.771) | 0.052 | — | — | Gender (female vs. male) | 1.001 (0.282-3.549) | 0.998 | — | — | Tumor diameter (≤4 vs. >4) | 1.364 (0.392-4.742) | 0.625 | — | — | TNM stage (I vs. II) | 2.832 (1.485-9.523) | 0.179 | — | — | Tumor grade (1/2 vs. 3/4) | 26.651 (7.081-100.313) | <0.001 | 14.506 (2.927-71.890) | 0.001 | Necrosis | 0.468 (0.058-3.752) | 0.475 | — | — | Sarcomatoid | 10.783 (3.117-37.306) | <0.001 | 24.145 (4.312-135.215) | <0.001 | SPON2 protein | 4.514 (1.736-11.741) | 0.002 | 0.402 (0.076-2.126) | 0.284 | SPON2 mRNA | 29.104 (3.672-230.684) | 0.001 | 61.060 (2.471-1508.739) | 0.012 |
|
|