Research Article

Association of Angiopoietin Dysregulation in Placental Malaria with Adverse Birth Outcomes

Table 1

Mother’s characteristics and birth outcomes by placental malaria status.

Malaria (-ve)
Malaria (+ve)

Characteristics of mother
 Agea0.27
  Axillary temperature (°C)a0.002
 Haemoglobin (g/dl)a<0.0001
 Anaemia89 (41%)49 (70%)<0.0001
 Primgravid72 (33.3%)25 (35.7%)
 Secundigravid71 (32.9%)22 (31.4%)
 Multigravid73 (33.8%)23 (32.9%)
 Angiopoietin (pg/ml)a
  Peripheral ANG1<0.0001
  Peripheral ANG2<0.0001
  Placental ANG1<0.0001
  Placental ANG2<0.0001
 Birth outcomes
  Normal83 (38.4%)28 (40.0%)
  Low birth weight86 (39.8%)25 (35.7%)
  Stillbirth47 (21.8%)17 (24.3%)
  Baby weight (gm)a#0.005

; indicates variable used to frequency match PM+ and PM- groups; values reported are Pearson chi-square test for categorical variable and two sample -test for continuous variables; #Birth weight information was collected for 53 babies born from PM+ and 169 babies born from PM- women.