Research Article

Sex-Specific Associations of Trimethylamine-N-Oxide and Zonulin with Signs of Depression in Carbohydrate Malabsorbers and Nonmalabsorbers

Table 2

Sex-specific correlations of TMAO and zonulin with the BDI-II score in individuals with and without CMA.

Study population ()CMA ()CMA ()CMA ()Non-CMA ()Non-CMA ()Non-CMA ()

TMAOTMAOTMAOTMAOTMAOTMAOTMAO
BDI-II score0.160a0.0400.0090.1280.2770.2740.315
0.011b,0.6710.9410.4170.0010.0100.027

ZonulinZonulinZonulinZonulinZonulinZonulinZonulin
BDI-II score0.0120.0350.0290.0430.0370.191- 0.269
0.8540.7120.8100.7850.6660.0770.062

BDI-II: Beck Depression Inventory; CMA: carbohydrate malabsorption; TMAO: trimethylamine-N-oxide. Spearman’s correlation analysis was calculated. aSpearman’s rho (); b value. A value < 0.05 was considered statistically significant.