Decreased Peripheral Blood ALKBH5 Correlates with Markers of Autoimmune Response in Systemic Lupus Erythematosus

Figure 1

Differential expression screening of METTL3, METTL14, WTAP, ALKBH5, FTO, and YTHDF2 in peripheral blood of SLE patients. (a) The level of METTL3 in peripheral blood was significantly decreased in SLE patients () compared to healthy controls (CON, ). (b) The level of METTL14 showed no significant difference between SLE patients () and CON (). (c) The level of WTAP in peripheral blood was significantly decreased in SLE patients () compared to CON (). (d) The level of ALKBH5 in peripheral blood was significantly decreased in SLE patients () compared to CON (). (e) The level of FTO in peripheral blood was significantly decreased in SLE patients () compared to CON (). (f) The level of YTHDF2 trends to decline in SLE patients, but a significant difference was not reached.

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