In Vitro and In Vivo Efficacy of DNA Damage Repair Inhibitor Veliparib in Combination with Artesunate against Echinococcus granulosus

Figure 3

Changes of cyst volume in experimentally infected mice by ultrasonography. The vesicles growth rate was assessed by determining T/C %. The model group received CMC-Na, and treatment groups were given Veliparib (25 mg/kg/d, p.o., q.d.). On days 1-14, AS-H (200 mg/kg/d) was administered 2 h after Veliparib. On days 1-30, ABZ (200 mg/kg/d), AS-L (50 mg/kg/d), and AS-H (200 mg/kg/d, p.o., q.d.) were administered.