Usefulness of Cathepsin S to Predict Risk for Obstructive Sleep Apnea among Patients with Type 2 Diabetes
Table 4
Association between levels of CTSS and variables in univariate and multiple linear regression models.
Univariate models
Multiple model (,)
Beta
95% CI
value
Beta
95% CI
value
Age (years)
-0.005
-51.183 to 48.343
0.955
0.034
-33.850 to 54.399
0.645
Sex (female vs. male)
0.186
124.692 to 2497.537
0.031
0.066
-603.815 to 1524.928
0.393
BMI (kg/m2)
0.116
-34.536 to 227.965
0.148
-0.054
-189.882 to 89.546
0.478
LVEF (%)
0.022
-69.687 to 91.954
0.786
AHI (events/h)
0.506
39.757 to 69.073
<0.001
0.386
21.988 to 57.781
<0.001
FBG (mmol/L)
0.444
602.300 to 1165.896
<0.001
0.340
328.871 to 921.777
<0.001
Total cholesterol (mmol/L)
0.075
-194.509 to 541.078
0.353
Triglyceride (mmol/L)
0.085
-158.839 to 527.189
0.291
LDL-C (mmol/L)
0.095
-204.688 to 815.319
0.239
hs-CRP (mg/L)
0.074
-59.811 to 161.904
0.364
Uric acid (μmol/L)
0.136
-0.594 to 8.440
0.088
-0.095
-7.434 to 1.876
0.239
ALT (U/L)
0.171
1.374 to 40.573
0.036
0.012
-17.892 to 20.757
0.883
GGT (U/L)
0.208
4.290 to 29.517
0.009
0.113
-3.932 to 21.711
0.172
Creatinine (μmol/L)
0.087
-9.832 to 33.883
0.279
Creatine kinase (U/L)
0.013
-3.387 to 3.966
0.877
The multiple linear regression model includes age, sex, BMI, and other variables with in univariate model analysis. : adjusted of the multiple linear regression model; CI: confidence intervals; CTSS: cathepsin S; BMI: body mass index; LVEF: left ventricular ejection fraction; AHI: apnea-hypopnea index; FBG: fasting blood glucose; LDL-C: low-density lipoprotein cholesterol; hs-CRP: high-sensitivity C-reactive protein; ALT: alanine aminotransferase; GGT: γ-glutamyl transferase.
