Review Article

The Role of Circulating RBP4 in the Type 2 Diabetes Patients with Kidney Diseases: A Systematic Review and Meta-Analysis

Table 1

Characteristics of included studies.

AuthorYearCountry/regionSample sizeSex (female/total)Age (year, )MethodSampleNOS
DMControlDMControl

Akbay2010Turkey8328/5321/31ELISASerum7
Chang2008Taiwan, China11154/9511/16ELISASerum8
Chu2011Taiwan, China23922/8663/153ELISASerum8
Klisic2020Serbia10624/4041/66ELISASerum7
Mahfouz2016Saudi Arabia20091/15035/50ELISASerum7
Masaki2008Japan5824/48NANAELISAPlasma7
Ni2018Mainland China19269/17213/20ELISASerum8
Park2014Republic of Korea689239/47141/75ELISASerum8
Raila2007Germany9732/6221/35NA49 (21-71)#ELISAPlasma7
Toruner2011Turkey8722/3927/48ELISASerum7
Wang2013Mainland China19037/120NANAELISAPlasma6
Xu2017Mainland China1795303/524479/763ELISASerum8

Abbreviations: DM: diabetes mellitus; NOS: Newcastle-Ottawa Scale; ELISA: enzyme-linked immunosorbent assay; NA: not available. Note: DM means DM with CKD, control means DM without CKD. #Data was expressed as median (range).