The Value of Haematological Parameters and Tumour Markers in the Prediction of Intestinal Obstruction in 1474 Chinese Colorectal Cancer Patients
Table 2
Baseline Clinicopathologic Characteristics of colorectal cancer patients.
OCC
Non-OCC
P
(n =238) (%)
(n =1236) (%)
Age(yr) (median ± qrange)
59.00 ± 15.00
58.50 ± 16.00
0.1162
Sex
Male
148 (62.18)
719 (58.17)
0.2493
Female
90 (37.82)
517 (41.83)
Smoke
No
176 (73.95)
995 (80.50)
0.0220
Yes
62 (26.05)
241 (19.50)
Tumor history
No
221 (92.86)
1097 (88.75)
0.0595
Yes
17 (7.14)
139 (11.25)
Tumor location
Left colon
129 (54.20)
894 (72.33)
<0.0001
Right colon
109 (45.80)
342 (27.67)
TNM
I
4 (1.68)
193 (15.61)
<0.0001
II
95 (39.92)
407 (32.93)
III
106 (44.54)
474 (38.35)
IV
33 (13.87)
162 (13.11)
Tumor size (cm)
d <4.5
105 (44.12)
751 (60.76)
<0.0001
4.5 ≤ d
133 (55.88)
485 (39.24)
Differentiation
Low
25 (10.50)
69 (5.58)
0.0044
High
213 (89.50)
1167 (94.42)
Circumferential margin
No
236 (99.17)
1224 (99.03)
0.8492
Yes
2 (0.83)
12 (0.97)
Vascular tumor thrombus
No
187 (78.57)
1022 (82.69)
0.1301
Yes
51 (21.43)
214 (17.31)
Nerve invasion
No
161 (70.17)
988 (79.94)
0.0008
Yes
71 (29.83)
248 (20.06)
Chemotherapy
No
132 (55.46)
560 (45.31)
0.0040
Yes
106 (44.54)
676 (54.69)
Radiotherapy
No
226 (94.96)
1165 (94.26)
0.6669
Yes
12 (5.04)
71 (5.74)
NEN(G/L) (median ± qrange)
3.79 ± 2.53
3.59 ± 1.77
0.0526
WBC(G/L) (median ± qrange)
5.80 ± 2.97
5.84 ± 2.23
0.5276
LYM(G/L) (median ± qrange)
1.30 ± 0.75
1.55 ± 0.68
<0.0001
CEA(ug/L) (median ± qrange)
5.23 ± 12.40
3.30 ± 6.30
<0.0001
CA19-9(U/ml) (median ± qrange)
11.60 ± 37.10
8.65 ± 18.50
0.0201
CA125(U/ml) (median ± qrange)
20.75 ± 35.10
11.40 ± 8.30
<0.0001
ALB(U/L) (median ± qrange)
38.15 ± 6.50
40.90 ± 6.10
<0.0001
ALP(U/L) (median ± qrange)
71.50 ± 27.00
75.00 ± 27.50
0.0403
GGT(U/L) (median ± qrange)
18.00 ± 15.00
19.00 ± 13.00
0.8573
Tp(U/L) (median ± qrange)
61.95 9.80
65.30 ± 9.40
<0.0001
NLR (median ± qrange)
2.78 ± 2.71
2.28 ± 1.58
<0.0001
P was calculated by the Wilcoxon test for continuous variables and the chi-square test for categorical variables. NEU, neutrophil; WBC, white blood cell; LYM, lymphocyte; CEA, carcinoembryonic antigen; CA19-9, carbohydrate antigen 19-9; CA125, cancer antigen 125; ALB, albumin; ALP, alkaline phosphatase; GGT, gamma-glutamyl transpeptidase; Tp, Total protein; NLR = neutrophil/lymphocyte.
