Research Article

TGFBR3 Polymorphisms (rs1805110 and rs7526590) Are Associated with Laboratory Biomarkers and Clinical Manifestations in Sickle Cell Anemia

Figure 1

Association of TGFBR3 rs1805110 polymorphism with laboratory biomarkers using the dominant genetic model. SCA individual carriers of the minor allele A (A/G+A/A) presented increased (a) hemoglobin, (b) hematocrit, (c) reticulocyte counts, (d) total cholesterol, (e) LDL-C, (f) uric acid, and (g) endothelin levels as well as (h) decreased PDW. All values obtained by the Mann–Whitney test, except for hemoglobin, hematocrit, and LDL-C, for which the independent -test was used.
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