Research Article

Association of the Sialylation of Antibodies Specific to the HCV E2 Envelope Glycoprotein with Hepatic Fibrosis Progression and Antiviral Therapy Efficacy

Table 1

The characteristics of patients under investigation .

HCV genotype ()Hepatic fibrosis stageResponse to treatment
01234SVRNRRLST
(%) (%) (%) (%) (%) (%) (%) (%) (%)

1b (51)26 (51)9 (17,6)5 (9,8)3 (5,9)8 (15,7)24 (47,1)10 (19,6)14 (27,5)3 (5,9)
3a (46)21 (45,7)14 (30,4)6 (13)1 (2,2)4 (8,7)37 (80,4)1 (2,2)5 (10,9)3 (6,5)
1a+2a/2c (6)4 (66,7)1 (16,7)1 (16,7)0 (0)0 (0)5 (83,3)0 (0)0 (0)1 (16,7)
All cases (103)51 (49,5)24 (23,3)12 (11,7)4 (3,9)12 (11,6)66 (64,1)11 (10,7)19 (18,5)7 (6,8)

Genotype 1a: one patient; GT 2a/2c: 5 patients. SVR: sustained virologic response; NR: no response, RL – relapse. In seven patients treatment was stopped (ST) due to intolerance.