The Key Genes Underlying Pathophysiology Association between Plaque Instability and Progression of Myocardial Infarction
Table 3
Top clusters with their representative enriched terms of gene lists between DEG4 and MI_1d.
GO
Category
Description
Count
%
log10()
GO:0006954
GO biological processes
Inflammatory response
27
19.01
-11.96
GO:0042110
GO biological processes
T cell activation
21
14.79
-10.16
GO:0002274
GO biological processes
Myeloid leukocyte activation
15
10.56
-10.10
R-MMU-6798695
Reactome gene sets
Neutrophil degranulation
20
14.08
-9.38
GO:0002250
GO biological processes
Adaptive immune response
20
14.08
-8.35
GO:0019221
GO biological processes
Cytokine-mediated signaling pathway
16
11.27
-8.22
GO:0060326
GO biological processes
Cell chemotaxis
14
9.86
-7.58
GO:0001906
GO biological processes
Cell killing
11
7.75
-6.83
GO:0002683
GO biological processes
Negative regulation of immune system process
16
11.27
-6.60
R-MMU-983695
Reactome gene sets
Antigen activates B cell receptor (BCR) leading to generation of second messengers
5
3.52
-6.35
GO:0002366
GO biological processes
Leukocyte activation involved in immune response
12
8.45
-6.14
ko04668
KEGG pathway
TNF signaling pathway
8
5.63
-6.11
GO:2000106
GO biological processes
Regulation of leukocyte apoptotic process
8
5.63
-6.02
GO:0002526
GO biological processes
Acute inflammatory response
8
5.63
-5.65
ko05152
KEGG pathway
Tuberculosis
9
6.34
-5.38
GO:0006909
GO biological processes
Phagocytosis
12
8.45
-5.13
R-MMU-109582
Reactome gene sets
Hemostasis
14
9.86
-4.96
GO:0033628
GO biological processes
Regulation of cell adhesion mediated by integrin
5
3.52
-4.89
GO:0031334
GO biological processes
Positive regulation of protein complex assembly
10
7.04
-4.67
GO:0009620
GO biological processes
Response to fungus
5
3.52
-4.53
“Count” is the number of genes in the user-provided lists with membership in the given ontology term. “%” is the percentage of all of the user-provided genes that are found in the given ontology term (only input genes with at least one ontology term annotation are included in the calculation). “log10()” is the value in log base 10.
