Ethacrynic Acid Enhances the Antitumor Effects of Afatinib in EGFR/T790M-Mutated NSCLC by Inhibiting WNT/Beta-Catenin Pathway Activation

<div>Combination of afatinib with EA suppressed tumor growth <i>in vivo</i>. (a) Image showing the method of tumor removal in a representative experiment. (b) The change in tumor volume of mice after treatment with different drugs. 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Disease Markers

fig3

Figure 3

Figure 3: Ethacrynic Acid Enhances the Antitumor Effects of Afatinib in EGFR/T790M-Mutated NSCLC by Inhibiting WNT/Beta-Catenin Pathway Activation 