Elevated Serum Small Dense Low-Density Lipoprotein Cholesterol May Increase the Risk and Severity of Coronary Heart Disease and Predict Cardiovascular Events in Patients with Type 2 Diabetes Mellitus
Table 6
sdLDL-C levels are related to the incidence of MACEs.
MACEs
Non-CHD group
CHD group
Low sdLDL-C ()
High sdLDL-C ()
Low sdLDL-C ()
High sdLDL-C ()
CHD
46 (6.70%)
48 (7.07%)
0.431
—
—
Cardiovascular deaths
0 (0%)
2 (0.29%)
0.247
21 (2.05%)
26 (2.51%)
0.293
Nonfatal MI
5 (0.73%)
10 (1.47%)
0.144
61 (5.96%)
87 (8.39%)
0.020
Nonfatal strokes
2 (0.29%)
7 (1.03%)
0.086
32 (3.13%)
39 (3.76%)
0.251
Heart failure
2 (0.29%)
3 (0.44%)
0.494
9 (0.88%)
14 (1.35%)
0.210
Hospitalized unstable angina
9 (1.31%)
18 (2.65%)
0.056
21 (2.05%)
22 (2.12%)
0.517
Total
64 (9.32%)
88 (12.96%)
0.020
144 (14.06%)
188 (18.13%)
0.007
sdLDL-C: small dense low-density lipoprotein cholesterol; CHD: coronary heart disease; MACEs: major cardiovascular events. Statistical analysis was performed with the chi-squared test for categorical variables.
