Research Article
Association of Polymorphisms in Vitamin D-Metabolizing Enzymes DHCR7 and CYP2R1 with Cancer Susceptibility: A Systematic Review and Meta-Analysis
Table 4
The results of Begg’s and Egger’s test for the publication bias.
| Comparison type | Begg’s test | Egger’s test | value | value | value | value |
| CYP2R1 rs10741657 (G/A) | | | | | Heterozygote vs. homozygote wild | 0 | 1 | -0.7 | 0.521 | Homozygote variant vs. homozygote wild | 0.38 | 0.707 | -0.73 | 0.503 | Dominant model | 0 | 1 | -0.53 | 0.627 | Recessive model | 0 | 1 | -0.29 | 0.787 | Allelic model | 0.75 | 0.452 | -0.38 | 0.722 | CYP2R1 rs12794714 (G/A) | | | | | Heterozygote vs. homozygote wild | 0.34 | 0.734 | 0.21 | 0.851 | Homozygote variant vs. homozygote wild | 1.02 | 0.308 | -2.84 | 0.105 | Dominant model | 0.34 | 0.734 | -0.01 | 0.994 | Recessive model | 1.7 | 0.089 | -9.45 | 0.011 | Allelic model | 0.34 | 0.734 | -1.12 | 0.38 | CYP2R1 rs2060793 (G/A) | | | | | Heterozygote vs. homozygote wild | 0 | 1 | NA | NA | Homozygote variant vs. homozygote wild | 0 | 1 | NA | NA | Dominant model | 0 | 1 | NA | NA | Recessive model | 0 | 1 | NA | NA | Allelic model | 0 | 1 | NA | NA | DHCR7 rs12785878 (T/G) | | | | | Heterozygote vs. homozygote wild | 0.24 | 0.806 | -1.64 | 0.2 | Homozygote variant vs. homozygote wild | -0.24 | 1 | -1.76 | 0.177 | Dominant model | -0.24 | 1 | -1.74 | 0.18 | Recessive model | 0.24 | 0.806 | -1.15 | 0.332 | Allelic model | 0.24 | 0.806 | -1.56 | 0.217 | DHCR7 rs1790349 (A/G) | | | | | Heterozygote vs. homozygote wild | 0 | 1 | 0.18 | 0.884 | Homozygote variant vs. homozygote wild | 0 | 1 | 0.13 | 0.92 | Dominant model | 0 | 1 | -0.44 | 0.737 | Recessive model | 0 | 1 | -2.34 | 0.257 | Allelic model | 1.04 | 0.296 | -0.9 | 0.532 |
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Note: the results are in bold if . |