Next-Generation Sequencing for Molecular Diagnosis of Cystic Fibrosis in a Brazilian Cohort

Figure 1

Flowchart of the studied sample. Of 198 probands with clinical suspicion of cystic fibrosis (CF), 74 candidates for next-generation sequencing (NGS) were part of an initial genetic screening of 27 variants. After the first stage, these patients were found to have one or no mutated CFTR allele. Additionally, 19 patients had not undergone any initial screening, totaling 93 patients.