Research Article
Clinical Value of Prognostic Nutritional Index and Neutrophil-to-Lymphocyte Ratio in Prediction of the Development of Sepsis-Induced Kidney Injury
Table 2
Univariate analyses of clinical and laboratory results between non-AKI group and S-AKI group within the first 24 h data.
| Variables | Total | Non-AKI | S-AKI | value | | | | |
| WBC (109/L) | 9.76 (6.47-14.73) | 9.15 (6.06-13.32) | 11.23 (7.03-16.32) | <0.001 | Neutrophil (109/L) | 8.16 (4.78-11.85) | 6.71 (4.12-9.70) | 10.02 (6.69-14.62) | <0.001 | Lymphocyte (109/L) | 0.81 (0.54-1.13) | 0.93 (0.64-1.24) | 0.67 (0.44-0.95) | <0.001 | Platelet (109/L) | 156.00 (99.00-228.00) | 167.00 (103.00-236.50) | 141.00 (85.00-210.00) | <0.001 | Monocyte (109/L) | 0.41 (0.25-0.65) | 0.40 (0.25-0.62) | 0.43 (0.25-0.68) | 0.090 | RDW (%) | 14.00 (13.00-15.60) | 13.90 (12.90-15.50) | 14.10 (13.10-15.70) | 0.129 | ALB (g/L) | 31.00 (27.40-34.43) | 32.60 (29.50-35.90) | 27.80 (25.10-31.30) | <0.001 | GLU (mmol/L) | 6.72 (5.19-9.68) | 6.66 (5.21-9.63) | 6.95 (5.10-9.82) | 0.650 | ALT (U/L) | 33.00 (20.00-69.00) | 30.00 (18.00-56.00) | 40.00 (22.00-89.00) | <0.001 | AST (U/L) | 35.00 (21.00-73.00) | 31.00 (20.00-56.00) | 42.00 (24.00-106.00) | <0.001 | TBIL (μmol/L) | 23.45 (13.10-56.00) | 21.20 (12.70-43.00) | 26.70 (14.30-70.70) | <0.001 | CRE (μmol/L) | 65.00 (4800-114.25) | 56.00 (44.00-77.00) | 101.00 (60.00-186.00) | <0.001 | BUN (mmol/L) | 7.21 (4.73-13.21) | 5.91 (4.18-9.24) | 11.77 (6.20-18.40) | <0.001 | UA (μmol/L) | 262.00 (178.75-365.00) | 232.00 (158.00-312.00) | 316.00 (217.00-443.00) | <0.001 | INR | 1.25 (1.11-1.46) | 1.22 (1.11-1.38) | 1.30 (1.13-1.59) | <0.001 | NLR | 10.07 (5.40-16.87) | 7.38 (4.22-12.41) | 14.86 (9.58-24.89) | <0.001 | PNI | 35.55 (31.65-38.80) | 37.00 (34.70-39.85) | 31.70 (31.10-35.85) | <0.001 | PLR | 200.00 (110.51-317.88) | 190.24 (108.98-297.01) | 213.79 (114.71-355.56) | 0.013 |
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WBC: white blood cell; RDW: red cell distribution width; ALB: albumin; GLU: glucose; ALT: alanine aminotransferase; AST: aspartate aminotransferase; TBIL: total bilirubin; CRE: creatinine; BUN: blood urea nitrogen; UA: uric acid; INR: international normalized ratio; NLR: neutrophil-to-lymphocyte ratio; PNI: prognostic nutrition index; PLR: platelet-to-lymphocyte ratio.
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