Research Article

Clinical Value of Prognostic Nutritional Index and Neutrophil-to-Lymphocyte Ratio in Prediction of the Development of Sepsis-Induced Kidney Injury

Table 2

Univariate analyses of clinical and laboratory results between non-AKI group and S-AKI group within the first 24 h data.

VariablesTotalNon-AKIS-AKI value

WBC (109/L)9.76 (6.47-14.73)9.15 (6.06-13.32)11.23 (7.03-16.32)<0.001
Neutrophil (109/L)8.16 (4.78-11.85)6.71 (4.12-9.70)10.02 (6.69-14.62)<0.001
Lymphocyte (109/L)0.81 (0.54-1.13)0.93 (0.64-1.24)0.67 (0.44-0.95)<0.001
Platelet (109/L)156.00 (99.00-228.00)167.00 (103.00-236.50)141.00 (85.00-210.00)<0.001
Monocyte (109/L)0.41 (0.25-0.65)0.40 (0.25-0.62)0.43 (0.25-0.68)0.090
RDW (%)14.00 (13.00-15.60)13.90 (12.90-15.50)14.10 (13.10-15.70)0.129
ALB (g/L)31.00 (27.40-34.43)32.60 (29.50-35.90)27.80 (25.10-31.30)<0.001
GLU (mmol/L)6.72 (5.19-9.68)6.66 (5.21-9.63)6.95 (5.10-9.82)0.650
ALT (U/L)33.00 (20.00-69.00)30.00 (18.00-56.00)40.00 (22.00-89.00)<0.001
AST (U/L)35.00 (21.00-73.00)31.00 (20.00-56.00)42.00 (24.00-106.00)<0.001
TBIL (μmol/L)23.45 (13.10-56.00)21.20 (12.70-43.00)26.70 (14.30-70.70)<0.001
CRE (μmol/L)65.00 (4800-114.25)56.00 (44.00-77.00)101.00 (60.00-186.00)<0.001
BUN (mmol/L)7.21 (4.73-13.21)5.91 (4.18-9.24)11.77 (6.20-18.40)<0.001
UA (μmol/L)262.00 (178.75-365.00)232.00 (158.00-312.00)316.00 (217.00-443.00)<0.001
INR1.25 (1.11-1.46)1.22 (1.11-1.38)1.30 (1.13-1.59)<0.001
NLR10.07 (5.40-16.87)7.38 (4.22-12.41)14.86 (9.58-24.89)<0.001
PNI35.55 (31.65-38.80)37.00 (34.70-39.85)31.70 (31.10-35.85)<0.001
PLR200.00 (110.51-317.88)190.24 (108.98-297.01)213.79 (114.71-355.56)0.013

WBC: white blood cell; RDW: red cell distribution width; ALB: albumin; GLU: glucose; ALT: alanine aminotransferase; AST: aspartate aminotransferase; TBIL: total bilirubin; CRE: creatinine; BUN: blood urea nitrogen; UA: uric acid; INR: international normalized ratio; NLR: neutrophil-to-lymphocyte ratio; PNI: prognostic nutrition index; PLR: platelet-to-lymphocyte ratio.