Disease Markers

Research Article

Clinical Value of Prognostic Nutritional Index and Neutrophil-to-Lymphocyte Ratio in Prediction of the Development of Sepsis-Induced Kidney Injury

Table 4

Association of PNI and NLR with AKI in sepsis patients.


Exposure	Nonadjusted OR	value	Adjusted OR	value

Model 1
PNI	0.799 (0.773-0.825)	<0.001	0.802 (0.776-0.829)	<0.001
NLR	1.094 (1.077-1.110)	<0.001	1.094 (1.078-1.111)	<0.001
Model 2
PNI	0.799 (0.773-0.825)	<0.001	0.801 (0.775-0.829)	<0.001
NLR	1.094 (1.077-1.110)	<0.001	1.097 (1.080-1.114)	<0.001
Model 3
PNI	0.799 (0.773-0.825)	<0.001	0.717 (0.666-0.772)	<0.001
NLR	1.094 (1.077-1.110)	<0.001	1.044 (1.016-1.072)	0.002

Model 1: adjusted for age and sex. Model 2: model 1 and diabetes, hypertension, cardiovascular disease, chronic liver disease, malignancy tumor, HR, RR, and MAP. Model 3: model 2 and WBC, neutrophil, lymphocyte, platelet, monocyte, RDW, ALB, GLU, AST, ALT, CRE, BUN, UA, and INR. HR: heart rate; RR: respiratory rate; MAP: mean arterial pressure; RDW: red cell distribution width; ALB: albumin; GLU: glucose; ALT: alanine aminotransferase; AST: aspartate aminotransferase; CRE: creatinine; BUN: blood urea nitrogen; UA: uric acid; INR: international normalized ratio.