Associations of Genetic Polymorphisms of mTOR rs2295080 T/G and rs1883965 G/A with Susceptibility of Urinary System Cancers

<div>The relationship of mTOR protein assessed by the STRING tools. At least 30 proteins can participate in the interaction with mTOR (a). The most relevant are RPS6KB1 (Ribosomal protein S6 kinase beta-1), LAMTOR5 (Ragulator complex protein), RHEB (GTP-binding protein), MAPKAP1 (Target of rapamycin complex 2 subunit), LAMTOR1 (Ragulator complex protein), RICTOR (Rapamycin-insensitive companion of mTOR), RPTOR (Regulatory-associated protein of mTOR), EIF4EBP1 (Eukaryotic translation initiation factor 4E-binding protein 1), LAMTOR4 (Ragulator complex protein 4), and LAMTOR2 (Ragulator complex protein 2) (b).</div>

Disease Markers

fig8

Figure 8

Figure 8: Associations of Genetic Polymorphisms of mTOR rs2295080 T/G and rs1883965 G/A with Susceptibility of Urinary System Cancers 