Research Article

Identification of Novel Diagnostic Biomarkers in Prostate Adenocarcinoma Based on the Stromal-Immune Score and Analysis of the WGCNA and ceRNA Network

Table 1

GO function and KEGG pathway analysis for differently expressed genes in the IS high group vs. IS low group and SS high group vs. SS low group.

GroupGOKEGG
Biology function valuePathway value

ISSignal transductionMetabolic pathways
Neutrophil degranulationFocal adhesion
Immune responsePathways in cancer
Innate immune responsePI3K-Akt signaling pathway
Oxidation-reduction processCell adhesion molecules (CAMs)

SSSignal transductionMetabolic pathways
ProteolysisFocal adhesion
Positive regulation of transcription from RNA polymerase II promoter0.001PI3K-Akt signaling pathway
Immune responsePathways in cancer
Cell adhesionECM-receptor interaction

IS: immune score; SS: stroma score; GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genome.