Research Article
Identification of CXCR4 Upregulation in Diffuse Large B-Cell Lymphoma Associated with Prognostic Significance and Clinicopathological Characteristics
Table 2
Relationship between CXCR4 expression status and clinicopathological features in DLBCL.
| | | CXCR4 negative | CXCR4 positive | value |
| Age | <60 ≥60 | 16 15 | 5 8 | 0.426 |
| Gender | Male Female | 17 14 | 9 4 | 0.376 |
| Ann Arbor stage | I-II III-IV | 17 14 | 5 8 | 0.322 |
| COO | GCB Non-GCB | 25 6 | 6 7 | 0.022 |
| IPI score | 0-1 ≥2 | 9 22 | 3 10 | 0.686 |
| MTOR | <20% ≥20% | 21 10 | 4 9 | 0.024 |
| CD5 | <50% ≥50% | 20 11 | 9 4 | 0.763 |
| CD8 + T cell infiltration | <20% ≥20% | 14 17 | 8 5 | 0.322 |
| C-MYC | <50% ≥50% | 15 16 | 8 5 | 0.426 |
| TP53 | <50% ≥50% | 21 10 | 6 7 | 0.180 |
| PD-1 | ≤1% >1% | 4 27 | 3 10 | 0.404 |
| PD-L1 | ≤1% >1% | 22 9 | 10 3 | 0.686 |
|
|
Abbreviations: COO: cell of origin.
|