The Effect of Artificial Liver Support System on Prognosis of HBV-Derived Hepatorenal Syndrome: A Retrospective Cohort Study

Table 7

Univariate and multivariate analysis of the difference of variates between post- and pre-ALSS groups as risk factors on 28-day mortality in patients treated with ALSS.

Variates	Univariate Cox regression		Multivariate Cox regression
	HR (95% CI)	value	HR (95% CI)	value
ΔSerum bilirubin	1.00 (1.00-1.00)	0.301
ΔALT	1.00 (1.00-1.00)	0.581
ΔNeutrophil	0.99 (0.98-1.00)	0.075
ΔINR	1.49 (1.12-1.98)	0.006	1.42 (1.06-1.90)	0.020
ΔCreatinine	1.00 (1.00-1.00)	0.003	1.00 (1.00-1.00)	0.016

ALT: alanine aminotransferase; INR: international normalized ratio.