Red Cell Distribution Width to Platelet Ratio Is Associated with Increasing In-Hospital Mortality in Critically Ill Patients with Acute Kidney Injury

Table 4

Subgroup analyses of the association between red cell distribution width to platelet ratio and in-hospital mortality in critically ill patients with acute kidney injury.

Variables		HR (95% CI)	value	for interaction
Age				0.075
≤65 years	10895	2.08 (1.93-2.25)	<0.001
>65 years	13271	1.24 (1.18-1.32)	<0.001
Gender				0.375
Male	13897	1.46 (1.38-1.55)	<0.001
Female	10269	1.52 (1.42-1.63)	<0.001
Ethnicity				0.803
Caucasian	17338	1.49 (1.41-1.157)	<0.001
Others	6828	1.49 (1.36-1.62)	<0.001
Congestive heart failure				<0.001
No	16343	1.70 (1.60-1.80)	<0.001
Yes	7823	1.24 (1.16-1.33)	<0.001
Chronic pulmonary				0.030
No	18407	1.54 (1.46-1.62)	<0.001
Yes	5759	1.35 (1.24-1.47)	<0.001
Diabetes				0.407
No	16579	1.52 (1.44-1.60)	<0.001
Yes	7587	1.45 (1.34-1.57)	<0.001
Obesity				0.455
No	22390	1.46 (1.40-1.53)	<0.001
Yes	1776	1.52 (1.23-1.88)	<0.001
Renal replacement therapy				0.019
No	22856	1.49 (1.42-1.56)	<0.001
Yes	1310	1.25 (1.08-1.46)	0.004
Mechanical ventilation				0.084
No	10709	1.55 (1.45-1.65)	<0.001
Yes	13457	1.44 (1.35-1.53)	<0.001
Vasopressor use				0.001
No	13634	1.64 (1.54-1.75)	<0.001
Yes	10532	1.35 (1.27-1.44)	<0.001
AKI stage				0.233
Stage 1	7010	1.57 (1.43-1.72)	<0.001
Stage 2	12015	1.44 (1.34-1.54)	<0.001
Stage 3	5141	1.36 (1.26-1.48)	<0.001

HR: hazard ratio; CI: confidence interval; AKI: acute kidney injury.