Research Article

Human Umbilical Cord Mesenchymal Stem Cell-Derived Extracellular Vesicles Carrying MicroRNA-29a Improves Ovarian Function of Mice with Primary Ovarian Insufficiency by Targeting HMG-Box Transcription Factor/Wnt/β-Catenin Signaling

Figure 5

HBP1 upregulation attenuates the inhibitory effects of miR-29a upregulation on the apoptosis of GC. (a–c) Overexpression efficiency of pcDNA3.1-HBP1 was identified by RT-qPCR and western blotting. (d, e) EdU of GC proliferation in the Exos-miR-NC group, the Exos-miR-29a group, and the Exos-miR-29a+Exos-HBP1 group. (f) CCK-8 of cell viability. (g, h) Flow cytometry of cell apoptosis. , , and .