Diagnostic Value of the Blood Neutrophil-to-Lymphocyte Ratio and Monocyte-to-Lymphocyte Ratio in Tibia Fracture-Related Infection

Table 1

Demographic features and laboratory findings of the participants.

	Control ()	FRI ()	value
Age (years)	39 (28, 50)	42 (28.50, 49)	0.976
Gender (male/female)	95/67	145/25	<0.001
WBCs (×10^9/L)	7.50 (6.10, 9.13)	7.13 (5.96, 8.34)	0.079
Neutrophils (×10^9/L)	4.83 (3.86, 6.93)	4.16 (3.17, 5.39)	<0.001
Lymphocytes (×10^9/L)	1.73 (1.46, 2.07)	2.05 (1.71, 2.50)	<0.001
Monocytes (×10^9/L)	0.47 (0.36, 0.64)	0.51 (0.40, 0.63)	0.174
RBCs (×10^12/L)	4.41 (4.09, 4.82)	4.72 (4.22, 5.05)	0.002
Hemoglobin (g/L)	133 (121, 145)	132.50 (114.75, 144.25)	0.251
Platelets (×10^9/L)	227 (188.75, 267.25)	278 (218.75, 353.25)	<0.001
CRP (mg/L)	2.90 (1.58, 8.82)	4.49 (1.72, 10.04)	0.244
ESR (mm/h)	25 (15, 41)	20 (8, 34.25)	0.005
NLR	2.73 (1.86, 4.35)	1.97 (1.40, 2.55)	<0.001
MLR	0.26 (0.19, 0.39)	0.24 (0.19, 0.32)	0.009
PLR	132.70 (105.49, 174.56)	133.31 (99.29, 174.05)	0.694
Positive rates of inflammation markers (events, %)
WBCs	30, 18.52%	14, 8.24%	0.006
CRP	50, 30.86%	53, 31.18%	0.951
ESR	121, 74.69%	97, 57.06%	0.001
Open fracture vs. closed fracture	15/147	126/44	<0.001
Single site vs. multiple sites	118/44	137/33	0.094
Positive rate of culture (events, %)		87, 51.18%
Monomicrobial infection vs. polymicrobial infection		67/20

FRI: fracture-related infection; WBCs: white blood cells; RBCs: red blood cells; NLR: neutrophil-to-lymphocyte ratio; MLR: monocyte-to-lymphocyte ratio; PLR: platelet-to-lymphocyte ratio; CRP: C-reactive protein; ESR: erythrocyte sedimentation rate.