Research Article

Downregulation of MCF2L Promoted the Ferroptosis of Hepatocellular Carcinoma Cells through PI3K/mTOR Pathway in a RhoA/Rac1 Dependent Manner

Figure 1

MCFL2 is involved in sorafenib-resistance in HCC. (a) MCF2L is significantly upregulated in HCC through analyzing the data from the public dataset The Cancer Genome Atlas (TCGA; https://cancergenome.nih.gov/). (b) The expression of MCF2L in paired HCC tissues. (c) MCF2L is significantly increased in HCC cells-treated with sorafenib both on mRNA (left panel) and protein (right panel) levels. ANT: adjacent normal tissue; .
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