Ontology ID Description GeneRatio BgRatio p.adjust geneID Count BP GO:0044786 Cell cycle DNA replication 12/362 71/18670 1.078E-08 3.864E-05 3.693E-05 LIG1/MCM2/MCM3/MCM5/MCM6/POLA1/POLD1/POLE/RFC1/RPA2/ZPR1/E2F8 12 BP GO:0033260 Nuclear DNA replication 10/362 60/18670 2.113E-07 0.0003699 0.0003535 LIG1/MCM2/MCM3/MCM5/MCM6/POLA1/POLD1/POLE/RFC1/RPA2 10 BP GO:0006260 DNA replication 20/362 274/18670 4.358E-07 0.0003699 0.0003535 BARD1/LIG1/MCM2/MCM3/MCM5/MCM6/NFIA/POLA1/POLD1/POLE/RBBP4/RFC1/RPA2/S100A11/CHAF1B/ZPR1/E2F8/RMI1/RAD9B/GEN1 20 BP GO:0045047 Protein targeting to ER 13/362 118/18670 4.907E-07 0.0003699 0.0003535 RPL13/RPL26/RPL27/RPL38/RPL39/RPL36A/RPS12/RPS17/RPS24/RPS25/RPS29/SEC61G/RPL36 13 BP GO:0000184 Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 13/362 120/18670 5.967E-07 0.0003699 0.0003535 EXOSC10/RPL13/RPL26/RPL27/RPL38/RPL39/RPL36A/RPS12/RPS17/RPS24/RPS25/RPS29/RPL36 13 BP GO:0030647 Aminoglycoside antibiotic metabolic process 5/362 10/18670 6.202E-07 0.0003699 0.0003535 AKR1C4/AKR1C1/AKR1C2/AKR1C3/AKR1B10 5 BP GO:0072599 Establishment of protein localization to endoplasmic reticulum 13/362 122/18670 7.226E-07 0.0003699 0.0003535 RPL13/RPL26/RPL27/RPL38/RPL39/RPL36A/RPS12/RPS17/RPS24/RPS25/RPS29/SEC61G/RPL36 13 BP GO:0006614 SRP-dependent cotranslational protein targeting to membrane 12/362 105/18670 9.104E-07 0.0004078 0.0003897 RPL13/RPL26/RPL27/RPL38/RPL39/RPL36A/RPS12/RPS17/RPS24/RPS25/RPS29/RPL36 12 BP GO:0006613 Cotranslational protein targeting to membrane 12/362 109/18670 1.364E-06 0.0005429 0.0005189 RPL13/RPL26/RPL27/RPL38/RPL39/RPL36A/RPS12/RPS17/RPS24/RPS25/RPS29/RPL36 12 BP GO:0006297 Nucleotide-excision repair, DNA gap filling 6/362 23/18670 3.893E-06 0.001395 0.0013332 LIG1/POLD1/POLE/RFC1/RPA2/XRCC1 6 BP GO:0070972 Protein localization to endoplasmic reticulum 13/362 147/18670 5.926E-06 0.0019304 0.0018448 RPL13/RPL26/RPL27/RPL38/RPL39/RPL36A/RPS12/RPS17/RPS24/RPS25/RPS29/SEC61G/RPL36 13 BP GO:1902969 Mitotic DNA replication 5/362 15/18670 6.822E-06 0.002037 0.0019467 LIG1/MCM2/MCM3/MCM6/POLA1 5 BP GO:0006261 DNA-dependent DNA replication 13/362 153/18670 9.182E-06 0.0025306 0.0024184 LIG1/MCM2/MCM3/MCM5/MCM6/POLA1/POLD1/POLE/RFC1/RPA2/ZPR1/E2F8/GEN1 13 BP GO:1902644 Tertiary alcohol metabolic process 5/362 19/18670 2.478E-05 0.0060658 0.005797 AKR1C4/AKR1C1/AKR1C2/AKR1C3/AKR1B10 5 BP GO:0006413 Translational initiation 14/362 193/18670 2.539E-05 0.0060658 0.005797 EIF4EBP1/MTOR/RPL13/RPL26/RPL27/RPL38/RPL39/RPL36A/RPS12/RPS17/RPS24/RPS25/RPS29/RPL36 14 BP GO:1901661 Quinone metabolic process 6/362 32/18670 3.016E-05 0.0067543 0.006455 AKR1C4/AKR1C1/AKR1C2/AKR1C3/AKR1B10/CYP4F11 6 BP GO:0016137 Glycoside metabolic process 5/362 20/18670 3.252E-05 0.0067919 0.0064909 AKR1C4/AKR1C1/AKR1C2/AKR1C3/AKR1B10 5 BP GO:0000082 G1/S transition of mitotic cell cycle 17/362 279/18670 3.412E-05 0.0067919 0.0064909 ANXA1/CASP2/CDKN2C/DHFR/EIF4EBP1/MCM2/MCM3/MCM5/MCM6/POLA1/POLE/RBL1/RPA2/RPL26/ZPR1/E2F8/DCUN1D3 17 BP GO:0000727 Double-strand break repair via break-induced replication 4/362 11/18670 4.119E-05 0.0077523 0.0074088 MCM2/MCM3/MCM5/MCM6 4 BP GO:0019083 Viral transcription 13/362 177/18670 4.327E-05 0.0077523 0.0074088 RPL13/RPL26/RPL27/RPL38/RPL39/RPL36A/RPS12/RPS17/RPS24/RPS25/RPS29/NUP62/RPL36 13 CC GO:0022626 Cytosolic ribosome 13/376 112/19717 2.22E-07 8.74E-05 8.22E-05 RPL13/RPL26/RPL27/RPL38/RPL39/RPL36A/RPS12/RPS17/RPS24/RPS25/RPS29/RPL36/RPL22L1 13 CC GO:0044445 Cytosolic part 17/376 247/19717 5.73E-06 0.00113 0.001062 EIF4EBP1/MTOR/RPL13/RPL26/RPL27/RPL38/RPL39/RPL36A/RPS12/RPS17/RPS24/RPS25/RPS29/TSC2/RPL36/CIAO2B/RPL22L1 17 CC GO:0022625 Cytosolic large ribosomal subunit 8/376 63/19717 2.52E-05 0.003307 0.00311 RPL13/RPL26/RPL27/RPL38/RPL39/RPL36A/RPL36/RPL22L1 8 CC GO:0042555 MCM complex 4/376 12/19717 5.71E-05 0.005622 0.005287 MCM2/MCM3/MCM5/MCM6 4 CC GO:0044391 Ribosomal subunit 13/376 190/19717 7.63E-05 0.006011 0.005653 RPL13/RPL26/RPL27/RPL38/RPL39/RPL36A/RPS12/RPS17/RPS24/RPS25/RPS29/RPL36/RPL22L1 13 CC GO:0042788 Polysomal ribosome 5/376 32/19717 0.000324 0.020848 0.019606 RPL38/RPL39/RPL36A/RPS29/RPL36 5 CC GO:0005657 Replication fork 7/376 70/19717 0.00037 0.020848 0.019606 DNMT1/MCM3/POLA1/POLD1/RFC1/RPA2/ZMIZ2 7 CC GO:0005753 Mitochondrial proton-transporting ATP synthase complex 4/376 22/19717 0.000725 0.035719 0.033591 ATP5F1E/ATP5MPL/PPIF/ATP5MD 4 CC GO:0045259 Proton-transporting ATP synthase complex 4/376 23/19717 0.000865 0.037488 0.035254 ATP5F1E/ATP5MPL/PPIF/ATP5MD 4 CC GO:0043601 Nuclear replisome 4/376 24/19717 0.001022 0.037488 0.035254 MCM3/POLA1/POLD1/RPA2 4 CC GO:0043596 Nuclear replication fork 5/376 41/19717 0.001047 0.037488 0.035254 MCM3/POLA1/POLD1/RPA2/ZMIZ2 5 CC GO:0030894 Replisome 4/376 26/19717 0.001396 0.038871 0.036555 MCM3/POLA1/POLD1/RPA2 4 CC GO:0005814 Centriole 9/376 139/19717 0.001411 0.038871 0.036555 CCNF/PCNT/STIL/CEP135/CEP104/WRAP73/NEDD1/CEP120/KIF24 9 CC GO:0022627 Cytosolic small ribosomal subunit 5/376 44/19717 0.001448 0.038871 0.036555 RPS12/RPS17/RPS24/RPS25/RPS29 5 CC GO:0001533 Cornified envelope 6/376 65/19717 0.00148 0.038871 0.036555 ANXA1/PI3/SPRR1B/SPRR2G/SPRR4/LCE3E 6 CC GO:0015934 Large ribosomal subunit 8/376 121/19717 0.002251 0.052932 0.049778 RPL13/RPL26/RPL27/RPL38/RPL39/RPL36A/RPL36/RPL22L1 8 CC GO:0005840 Ribosome 13/376 272/19717 0.002284 0.052932 0.049778 RPL13/RPL26/RPL27/RPL38/RPL39/RPL36A/RPS12/RPS17/RPS24/RPS25/RPS29/RPL36/RPL22L1 13 CC GO:0000784 Nuclear chromosome, telomeric region 8/376 125/19717 0.002757 0.05825 0.05478 MCM2/MCM3/MCM5/MCM6/POLD1/RPA2/XRCC1/CBX5 8 CC GO:0016469 Proton-transporting two-sector ATPase complex 5/376 51/19717 0.002809 0.05825 0.05478 ATP5F1E/ATP6V1F/ATP5MPL/PPIF/ATP5MD 5 CC GO:0044450 Microtubule organizing center part 10/376 185/19717 0.002993 0.058965 0.055452 CCNF/PCNT/STIL/CEP135/CEP104/WRAP73/SSX2IP/NEDD1/CEP120/KIF24 10 MF GO:0004032 Alditol:NADP+1-oxidoreductase activity 6/361 13/17697 1.05E-07 3.66E-05 3.34E-05 AKR1C4/AKR1C1/AKR1C2/AKR1C3/AKR1B10/AKR1B15 6 MF GO:0008106 Alcohol dehydrogenase (NADP+) activity 7/361 21/17697 1.26E-07 3.66E-05 3.34E-05 AKR1C4/AKR1C1/AKR1C2/AKR1C3/RDH8/AKR1B10/AKR1B15 7 MF GO:0004033 Aldo-keto reductase (NADP) activity 7/361 26/17697 6.53E-07 0.000126 0.000115 AKR1C4/AKR1C1/AKR1C2/AKR1C3/RDH8/AKR1B10/AKR1B15 7 MF GO:0016229 Steroid dehydrogenase activity 7/361 35/17697 5.7E-06 0.000827 0.000755 AKR1C4/AKR1C1/AKR1C2/HSD17B1/AKR1C3/RDH8/AKR1B15 7 MF GO:0033764 Steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 6/361 29/17697 2.21E-05 0.002561 0.002338 AKR1C4/AKR1C1/HSD17B1/AKR1C3/RDH8/AKR1B15 6 MF GO:0052650 NADP-retinol dehydrogenase activity 4/361 11/17697 5.02E-05 0.00485 0.004428 AKR1C3/RDH8/AKR1B10/AKR1B15 4 MF GO:0003688 DNA replication origin binding 5/361 24/17697 0.000106 0.00879 0.008024 MCM2/MCM3/MCM5/MCM6/POLA1 5 MF GO:0016616 Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 10/361 119/17697 0.000163 0.011845 0.010813 AKR1C4/AKR1C1/AKR1C2/HSD17B1/ME1/AKR1C3/RDH8/AKR1B10/PRXL2B/AKR1B15 10 MF GO:0003735 Structural constituent of ribosome 13/361 202/17697 0.00027 0.017192 0.015694 RPL13/RPL26/RPL27/RPL38/RPL39/RPL36A/RPS12/RPS17/RPS24/RPS25/RPS29/RPL36/RPL22L1 13 MF GO:0016614 Oxidoreductase activity, acting on CH-OH group of donors 10/361 128/17697 0.000296 0.017192 0.015694 AKR1C4/AKR1C1/AKR1C2/HSD17B1/ME1/AKR1C3/RDH8/AKR1B10/PRXL2B/AKR1B15 10 MF GO:0016651 Oxidoreductase activity, acting on NAD(P)H 9/361 107/17697 0.000343 0.018063 0.01649 AKR1C4/AKR1C1/AKR1C2/NQO1/NDUFB2/TXN/AKR1C3/TXNDC17/CYB5RL 9 MF GO:0008408 3 6/361 55/17697 0.000863 0.041702 0.038069 EXOSC10/POLD1/POLE/REXO2/EXO5/RAD9B 6 MF GO:0016796 Exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5 6/361 57/17697 0.001044 0.043249 0.039482 EXOSC10/POLD1/POLE/REXO2/EXO5/GEN1 6 MF GO:0016895 Exodeoxyribonuclease activity, producing 5 4/361 23/17697 0.001109 0.043249 0.039482 POLD1/POLE/EXO5/GEN1 4 MF GO:0016709 Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 5/361 39/17697 0.001119 0.043249 0.039482 AKR1C4/AKR1C1/AKR1C2/AKR1C3/CYP4F11 5 MF GO:0004303 Estradiol 17-beta-dehydrogenase activity 3/361 11/17697 0.00123 0.044091 0.04025 HSD17B1/RDH8/AKR1B15 3 MF GO:0004527 Exonuclease activity 7/361 81/17697 0.001322 0.044091 0.04025 EXOSC10/POLD1/POLE/REXO2/EXO5/RAD9B/GEN1 7 MF GO:0016655 Oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 6/361 60/17697 0.001368 0.044091 0.04025 AKR1C4/AKR1C1/AKR1C2/NQO1/NDUFB2/AKR1C3 6 MF GO:0140097 Catalytic activity, acting on DNA 12/361 213/17697 0.001472 0.044502 0.040626 DNMT1/LIG1/MCM2/MCM3/MCM5/MCM6/POLA1/POLD1/POLE/XRCC1/EXO5/GEN1 12 MF GO:0004529 Exodeoxyribonuclease activity 4/361 25/17697 0.001535 0.044502 0.040626 POLD1/POLE/EXO5/GEN1 4 KEGG hsa03030 DNA replication 10/166 36/8076 1.65E-09 3.85E-07 3.6E-07 LIG1/MCM2/MCM3/MCM5/MCM6/POLA1/POLD1/POLE/RFC1/RPA2 10 KEGG hsa03010 Ribosome 13/166 158/8076 2.04E-05 0.00239 0.002236 RPL13/RPL26/RPL27/RPL38/RPL39/RPL36A/RPS12/RPS17/RPS24/RPS25/RPS29/RPL36/RPL22L1 13 KEGG hsa04210 Apoptosis 10/166 136/8076 0.000471 0.036711 0.03435 CASP2/CTSL/LMNB1/NGF/PIK3CB/TRAF2/TUBA4A/PIK3R3/MAP3K14/BCL2L11 10 KEGG hsa03430 Mismatch repair 4/166 23/8076 0.001123 0.065715 0.061488 LIG1/POLD1/RFC1/RPA2 4 KEGG hsa00790 Folate biosynthesis 4/166 26/8076 0.001808 0.084601 0.079159 DHFR/PTS/AKR1C3/AKR1B10 4
