Extensive HPV Genotyping Reveals High Association between Multiple Infections and Cervical Lesions in Chinese Women

Table 1

Comparing single- (S-) and multiple- (M-) infection patterns of hr/phrHPV genotypes.

Genotypes	Infection	CIN2+ (/%)		Not CIN2+ (/%)
HPV16+	S	391	40.2%	582	59.8%	11.447	0.001
	M	193	31.7%	415	68.3%
HPV52+	S	106	8.3%	1171	91.7%	25.810	<0.001
	M	142	15.2%	792	84.8%
HPV53+	S	5	1.0%	507	99.0%	39.422	<0.001
	M	64	9.7%	598	90.3%
HPV56+	S	8	2.0%	386	98.0%	25.310	<0.001
	M	46	10.7%	383	89.3%
HPV51+	S	13	4.4%	285	95.6%	8.170	0.005
	M	38	10.3%	332	89.7%
HPV39+	S	6	1.8%	331	98.2%	21.196	<0.001
	M	36	10.1%	319	89.9%
HPV66+	S	3	1.1%	275	98.9%	26.296	<0.001
	M	37	11.6%	282	88.4%
HPV59+	S	3	1.1%	267	98.9%	26.228	<0.001
	M	37	11.9%	274	88.1%
HPV68+	S	5	1.6%	302	98.4%	21.503	<0.001
	M	33	10.6%	279	89.4%
HPV35+	S	4	2.9%	134	97.1%	7.479	0.006
	M	21	11.0%	181	89.0%
HPV58+	S	112	14.3%	670	85.7%	1.892	0.176
	M	101	17.0%	492	83.0%
HPV33+	S	64	23.6%	207	76.4%	1.899	0.182
	M	85	28.7%	211	71.3%
HPV31+	S	33	16.3%	169	83.7%	0.334	0.609
	M	41	18.5%	181	81.5%
HPV18+	S	38	14.0%	234	86.0%	0.447	0.521
	M	31	12.0%	227	88.0%
HPV45+	S	6	11.5%	46	88.5%	0.041	1.000
	M	11	10.5%	94	89.5%
HPV26+	S	6	26.1%	17	73.9%	0.000	1.000
	M	11	26.2%	31	73.8%
HPV82+	S	5	10.9%	41	89.1%	0.288	0.779
	M	10	14.3%	65	85.7%
HPV73+	S	0	0.0%	28	100.0%	2.025	0.299
	M	4	6.9%	54	93.1%

Not CIN2+, NILM, or LSIL.