The Bridging Effect of Controlled-Release Glial Cell-Derived Neurotrophic Factor Microcapsules within Nerve Conduits on Rat Facial Nerve Regeneration

Figure 2

Distribution of motor neurons from the zygomatic branch and the buccal branch at the facial nerve nucleus. The blue color shows motor neurons of the buccal branch of the facial nerve stained with FG. The red color shows DIL-stained zygomatic motor neurons of the facial nerve. The claret color demonstrates the double-labeled neurons. (a) Normal distribution of motor neurons from the zygomatic branch and the buccal branch motor neurons; (b) normal control group (nerve conduit filled with water); (c) testing group with the nerve conduit filled with GDNF solution; (d) testing group with the nerve conduit filled with GDNF microcapsule; (e) summary of total regenerated neurons. ; (f) summary of total incorrectly regenerated neurons. ; (g) summary of double-labeled neurons; (h) summary of the total incorrect regeneration ratio. .

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)