Disease Markers

Microvessel Structure and Microvascular Alterations in Chronic Diseases


Publishing date
01 Mar 2022
Status
Closed
Submission deadline
22 Oct 2021

Lead Editor

1The First Affiliated Hospital of Nanchang University, Nanchang, China

2Zhongshan Ophthalmic Center, Guangzhou, China

3Harvard Medical School, Boston, USA

4West China Medical Center of Sichuan University, Chengdu, China

5University of Miami Miller School of Medicine, Miami, USA

6Fudan University, Shanghai, China

This issue is now closed for submissions.
More articles will be published in the near future.

Microvessel Structure and Microvascular Alterations in Chronic Diseases

This issue is now closed for submissions.
More articles will be published in the near future.

Description

Microcirculation is the most basic structure of the circulatory system. It is the main location for material exchange between blood and tissues. Blood microcirculation refers to blood circulation in the capillaries between arterioles and venules. Microcirculation disorders are one of the important pathophysiological bases of chronic diseases. Improving microcirculation disorders is of great significance for the prevention, delay, and treatment of various chronic diseases. For instance, there is a need to focus on studying the mechanism of microcirculation disorders in chronic diseases, such as analyzing clinical manifestations and focusing on the clinical evidence and principles for improving microcirculation disorders. Studying microvessel structure and microvascular alterations as biomarkers can provide a certain reference for clinicians to rationally choose drugs to improve microcirculation disorders in chronic diseases. New clinical evidence can help with the treatment of chronic disease microcirculation disorders.

Many chronic diseases (e.g., diabetes, hypertension, glaucoma) are related to microcirculation disorders. Monitoring the changes of microcirculation is helpful to clinically understand the occurrence and development of diseases and the prognosis of treatment. Common surface microcirculation measuring instruments mainly include nailfold microcirculation electron microscope, laser scanning Doppler blood flow meter, television (TV) microscope, etc. These inspections are noninvasive and can be used to monitor and follow up on chronic diseases. It helps clinicians treat microcirculation disorders in patients. Moreover, it provides early diagnosis, early prevention, and treatment in clinical practice. Early treatment improves the prognosis of chronic diseases. However, ways for improving microcirculation disorders are still lacking sufficient evidence-based medical evidence. More basic research and related large-scale prospective clinical studies are still needed in the future to improve clinical applications.

The aim of this Special Issue is to bring together original research and review articles that discuss microvessel structure and microvascular alterations in chronic diseases.

Potential topics include but are not limited to the following:

  • Microvessel structure in chronic diseases
  • Microvascular alterations in chronic diseases
  • Underlying mechanisms of microvascular alterations
  • Biomarkers or specific signs for chronic microvascular alterations
  • Novel examinations in microvessels
  • Microvascular alterations before and after medical treatment
  • Novel treatments based on examining microvascular alterations in chronic diseases

Articles

  • Special Issue
  • - Volume 2022
  • - Article ID 8550714
  • - Research Article

Grey Matter Hypertrophy and Atrophy in Early-Blind Adolescents: A Surface-Based Morphometric Study

Fen Hou | Hengguo Li | ... | Xia Liu
  • Special Issue
  • - Volume 2022
  • - Article ID 9647706
  • - Research Article

Altered White Matter Integrity in Patients with Retinal Vein Occlusion: A Diffusion Tensor Imaging and Tract-Based Spatial Statistics Study

Mou-Xin Zhang | Min-Jie Chen | ... | Yi Shao
  • Special Issue
  • - Volume 2022
  • - Article ID 7729968
  • - Research Article

IDH1 Mutation Induces HIF-1α and Confers Angiogenic Properties in Chondrosarcoma JJ012 Cells

Xiaoyu Hu | Luyuan Li | ... | Jonathan C. Trent
  • Special Issue
  • - Volume 2022
  • - Article ID 1946104
  • - Research Article

Sequential and Dynamic Variations of IL-6, CD18, ICAM, TNF-α, and Microstructure in the Early Stage of Diabetic Retinopathy

Ang Xiao | HuiFeng Zhong | ... | Qiong Zhou
  • Special Issue
  • - Volume 2022
  • - Article ID 6530934
  • - Research Article

Cinnamaldehyde Downregulation of Sept9 Inhibits Glioma Progression through Suppressing Hif-1α via the Pi3k/Akt Signaling Pathway

Zhiwen Wang | Changfeng Wang | ... | Xinhui Zhou
  • Special Issue
  • - Volume 2022
  • - Article ID 9431044
  • - Research Article

Analysis of Macular Retinal Thickness and Microvascular System Changes in Children with Monocular Hyperopic Anisometropia and Severe Amblyopia

Lin-Lin Liu | Yu-Chuan Wang | ... | Hui Wang
  • Special Issue
  • - Volume 2021
  • - Article ID 2080962
  • - Research Article

Association of Iris Structural Measurements with Corneal Biomechanics in Myopic Eyes

Lin Fu | Yufeng Ye | ... | Qi Dai
  • Special Issue
  • - Volume 2021
  • - Article ID 2629150
  • - Research Article

Transneuronal Degeneration in the Visual Pathway of Rats following Acute Retinal Ischemia/Reperfusion

Yanyan Fu | Tu Hu | ... | Dan Wen
  • Special Issue
  • - Volume 2021
  • - Article ID 2135942
  • - Research Article

The Role of Conjunctival Microvasculation Combined with Echocardiography in Evaluating Pulmonary Arterial Hypertension in Systemic Lupus Erythematosus

Jiangbiao Xiong | Shujiao Yu | ... | Rui Wu
  • Special Issue
  • - Volume 2021
  • - Article ID 5866267
  • - Research Article

Association between Iris Biological Features and Corneal Biomechanics in Myopic Eyes

Lin Fu | Qi Dai | ... | Yufeng Ye
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Article of the Year Award: Outstanding research contributions of 2021, as selected by our Chief Editors. Read the winning articles.