Disease Markers

Possible Biomarkers in Malignant and Benign Neurological Disease 2021


Publishing date
01 Mar 2022
Status
Closed
Submission deadline
15 Oct 2021

Lead Editor

1Chinese Academy of Medical Sciences, Beijing, China

2Rehabilitation Hospital Affiliated to National Research Center for Rehabilitation Technical Aids, Beijing, China

3Manchester Metropolitan University, Manchester, UK

4Capital Medical University Beijing Tiantan Hospital, Beijing, China

This issue is now closed for submissions.
More articles will be published in the near future.

Possible Biomarkers in Malignant and Benign Neurological Disease 2021

This issue is now closed for submissions.
More articles will be published in the near future.

Description

A neurological disorder is any disorder of the nervous system. Structural, biochemical, or electrical abnormalities in the brain, spinal cord or other nerves can result in a range of symptoms. Biomarkers provide a dynamic and powerful approach to understanding the spectrum of neurological disease with applications in observational and analytic epidemiology, randomized clinical trials, screening, diagnosis and prognosis. Defined as alterations in the constituents of tissues or body fluids, these markers offer the means for homogeneous classification of a disease and risk factors, and they can extend our knowledge about the underlying pathogenesis of disease. Biomarkers can also reflect the entire spectrum of disease from the earliest manifestations to the terminal stages. Careful assessment of the validity of biomarkers is required with respect to the stage of disease. Causes of variability in the measurement of biomarkers range from the individual to the laboratory.

For certain neurological disorders, such as Glioma, Stroke, Parkinson's disease, Alzheimer's, and autism, diagnostic and prognostic biomarkers are yet to be established. These challenges warrant the active discovery of biomarkers which form the basis for accurate and less invasive diagnostic approaches as well as for individualized therapies for these disorders.

In this Special Issue, we call for research and review articles on the innovation and clinical application of biomarkers for malignant and benign neurological diseases. Research papers reporting multidisciplinary findings, such as those involving in preclinical/clinical validation, are especially welcome.

Potential topics include but are not limited to the following:

  • Diagnostic and prognostic markers associated with malignant and benign neurological diseases
  • Biomarkers and drug resistance in malignant and benign neurological disease
  • Biomarkers and malignant and benign neurological disease progression/development/risk
  • Biomarker discovery in malignant and benign neurological disease
  • Gut flora and biomarkers in malignant and benign neurological disease
  • Basic to clinical research

Articles

  • Special Issue
  • - Volume 2022
  • - Article ID 4660217
  • - Research Article

lncRNA DARS-AS1 Promoted Osteosarcoma Progression through Regulating miR-532-3p/CCR7

Yan Xue | Hongmiao Liu | ... | Xiaoping Ren
  • Special Issue
  • - Volume 2022
  • - Article ID 2395269
  • - Review Article

Tumor Necrosis Factor-α: The Next Marker of Stroke

Yimeng Xue | Xianwei Zeng | ... | Jizong Zhao
  • Special Issue
  • - Volume 2021
  • - Article ID 7115254
  • - Research Article

Intraoperative Use of Topical Retropharyngeal Steroids for Dysphagia after Anterior Cervical Fusion: A Systematic Review and Meta-Analysis

Hang Yu | Hui Dong | ... | Yongxiang Wang
  • Special Issue
  • - Volume 2021
  • - Article ID 3977189
  • - Research Article

CircLDLR Promotes Papillary Thyroid Carcinoma Tumorigenicity by Regulating miR-637/LMO4 Axis

Yuan-ming Jiang | Wei Liu | ... | Hongbin Chang
  • Special Issue
  • - Volume 2021
  • - Article ID 7933453
  • - Research Article

IL-38 and IL-36 Target Autophagy for Regulating Synoviocyte Proliferation, Migration, and Invasion in Rheumatoid Arthritis

Zhe Hao | Yi Liu
  • Special Issue
  • - Volume 2021
  • - Article ID 7157109
  • - Research Article

mtDNA in the Pathogenesis of Cardiovascular Diseases

Lili Wang | Qianhui Zhang | ... | Jing Yuan
  • Special Issue
  • - Volume 2021
  • - Article ID 3579074
  • - Research Article

Recanalization Treatment of Acute Ischemic Stroke Caused by Large-Artery Occlusion in the Elderly: A Comparative Analysis of “the Elderly” and “the Very Elderly”

Qi Wang | Yi-Qun Zhang | ... | Wei-Jian Jiang
  • Special Issue
  • - Volume 2021
  • - Article ID 7107705
  • - Research Article

H19 Overexpression Improved Efficacy of Mesenchymal Stem Cells in Ulcerative Colitis by Modulating the miR-141/ICAM-1 and miR-139/CXCR4 Axes

Ming-li Zhao | Tao Chen | ... | Xiao Wan
  • Special Issue
  • - Volume 2021
  • - Article ID 9953858
  • - Research Article

Association between Plasma Homocysteine Concentrations and the First Ischemic Stroke in Hypertensive Patients with Obstructive Sleep Apnea: A 7-Year Retrospective Cohort Study from China

Nanfang Li | Xintian Cai | ... | Qin Luo
  • Special Issue
  • - Volume 2021
  • - Article ID 6803510
  • - Research Article

Effect of ORF7 of SARS-CoV-2 on the Chemotaxis of Monocytes and Neutrophils In Vitro

Gang Wang | Jun Guan | ... | Zhi Chen
Disease Markers
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Article of the Year Award: Outstanding research contributions of 2021, as selected by our Chief Editors. Read the winning articles.