Stress is currently recognized as a major risk factor for several chronic diseases and may account for more than 75% of all visits to primary care physicians. Thus, the investigation of biomarkers and mechanisms involved in the pathophysiology of stress-related chronic conditions is of great relevance to the effort of preventing and reducing disease burden, as well as treating and monitoring disease evolution.

We invite researchers to submit high quality manuscripts reporting original research results and review articles related to the scientific advances in the area of stress-related chronic diseases. We encourage submissions covering the role of biomarkers on aspects such as risk estimation, susceptibility factors, diagnosis, disease staging, prognosis, prediction of treatment response/resistance, and mechanisms of disease pathophysiology. This issue will provide our readers with a better understanding of the importance of biomarkers in stress-related chronic diseases and will unveil the recent advancements in this area.

Potential topics include but are not limited to the following:

• Anxiety, depression, and other neuropsychiatric disorders
• Neurodegenerative disorders
• Hypertension and other cardiovascular diseases
• Diabetes and metabolic syndrome
• Cancer
• Peptic ulcer and alcohol abuse-induced cirrhosis