Disease Markers

Possible Biomarkers in Malignant and Benign Neurological Disease


Publishing date
01 Mar 2021
Status
Closed
Submission deadline
16 Oct 2020

Lead Editor

1Chinese Academy of Medical Sciences, Beijing, China

2Shandong University Qilu Hospital, Jinan, China

3Manchester Metropolitan University, Manchester, UK

4Capital Medical University Beijing Tiantan Hospital, Beijing, China

This issue is now closed for submissions.
More articles will be published in the near future.

Possible Biomarkers in Malignant and Benign Neurological Disease

This issue is now closed for submissions.
More articles will be published in the near future.

Description

A neurological disorder is any disorder of the nervous system. Structural, biochemical or electrical abnormalities in the brain, spinal cord or other nerves can result in a range of symptoms. Biomarkers provide a dynamic and powerful approach to understanding the spectrum of neurological disease with applications in observational and analytic epidemiology, randomized clinical trials, screening, diagnosis and prognosis. Defined as alterations in the constituents of tissues or body fluids, these markers offer the means for homogeneous classification of a disease and risk factors, and they can extend our knowledge about the underlying pathogenesis of disease. Biomarkers can also reflect the entire spectrum of disease from the earliest manifestations to the terminal stages. Careful assessment of the validity of biomarkers is required with respect to the stage of disease. Causes of variability in the measurement of biomarkers range from the individual to the laboratory.

For certain neurological disorders, such as Glioma, Stroke, Parkinson's disease, Alzheimer's and autism, diagnostic and prognostic biomarkers are yet to be established. These challenges warrant the active discovery of biomarkers which form the basis for accurate and less invasive diagnostic approaches as well as for individualized therapies for these disorders.

In this Special Issue, we call for research and review articles on the innovation and clinical application of biomarkers for malignant and benign neurological diseases. Research papers reporting multidisciplinary findings, such as those involving in preclinical/clinical validation, are especially welcome.

Potential topics include but are not limited to the following:

  • Diagnostic and prognostic markers associated with malignant and benign neurological diseases
  • Biomarkers and drug resistance in malignant and benign neurological disease
  • Biomarkers and malignant and benign neurological disease progression/development/risk
  • Biomarker discovery in malignant and benign neurological disease
  • Gut flora and biomarkers in malignant and benign neurological disease
  • Basic to clinical research

Articles

  • Special Issue
  • - Volume 2021
  • - Article ID 8862299
  • - Research Article

Homocysteine Level and Risk of Hemorrhage in Brain Arteriovenous Malformations

Chaofan Zeng | Fa Lin | ... | Jizong Zhao
  • Special Issue
  • - Volume 2021
  • - Article ID 8831948
  • - Research Article

The Genetic and Epigenetic Mechanisms Involved in Irreversible Pulp Neural Inflammation

Xiaoxi Xi | Yihong Ma | ... | Xianda Hu
  • Special Issue
  • - Volume 2021
  • - Article ID 8889569
  • - Research Article

Differentially Expressed Circular RNA Profile in an Intracranial Aneurysm Group Compared with a Healthy Control Group

Yonggang Ma | Baoqing Zhang | ... | Jizong Zhao
  • Special Issue
  • - Volume 2020
  • - Article ID 6630659
  • - Research Article

Identification of miRNAs as the Crosstalk in the Interaction between Neural Stem/Progenitor Cells and Endothelial Cells

Xin Wang | Simin Li | ... | Zhiqiang Su
  • Special Issue
  • - Volume 2020
  • - Article ID 8861358
  • - Research Article

Responsive Expression of MafF to β-Amyloid-Induced Oxidative Stress

Xiaoxuan Wang | Yu Zhang | ... | Liang Li
  • Special Issue
  • - Volume 2020
  • - Article ID 6661475
  • - Research Article

Prognostic Significance of Homocysteine Level on Neurological Outcome in Brain Arteriovenous Malformations

Fa Lin | Chaofan Zeng | ... | Jizong Zhao
  • Special Issue
  • - Volume 2020
  • - Article ID 8888085
  • - Research Article

FAM225B Is a Prognostic lncRNA for Patients with Recurrent Glioblastoma

Junsheng Li | Qian Zhang | ... | Jizong Zhao
  • Special Issue
  • - Volume 2020
  • - Article ID 8895968
  • - Research Article

Analysis of Long Noncoding RNA ZNF667-AS1 as a Potential Biomarker for Diagnosis and Prognosis of Glioma Patients

Qin Yuan | Chao Gao | ... | Tian-bao Lai
  • Special Issue
  • - Volume 2020
  • - Article ID 8844313
  • - Review Article

Explicating the Pivotal Pathogenic, Diagnostic, and Therapeutic Biomarker Potentials of Myeloid-Derived Suppressor Cells in Glioblastoma

Seidu A. Richard
  • Special Issue
  • - Volume 2020
  • - Article ID 6612871
  • - Research Article

Elevated Levels of Serum Neurofilament Light Chain Associated with Cognitive Impairment in Vascular Dementia

Weibin Ma | Jingjing Zhang | ... | Fengyu Zhang
Disease Markers
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Acceptance rate34%
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Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.