Dataset Paper

Alterations of Hormone-Sensitive Adenylyl Cyclase System in the Tissues of Rats with Long-Term Streptozotocin Diabetes and the Influence of Intranasal Insulin

Figure 2

The stimulating effects of hormones on AC activity in (a) the heart, (b) brain, and (c) testes of diabetic and control rats with and without therapy by I-I. C: control animals; CI: control animals treated with intranasal insulin (I-I); D: diabetic animals with 210-day streptozotocin-induced diabetes mellitus of the type 1 (T1DM); DI: diabetic animals treated with I-I. Isoproterenol, noradrenaline, serotonin, EMD-386088, and dopamine were taken at 10−5 M, PACAP-38 at 10−7 M, and hCG at 10−8 M. Values are the weighted mean ± weighted standard deviation of three individual experiments, each performed in triplicate. ** and *** denote the statistically significant difference between Groups C and D at and 0.001; #, ##, and ###, the same between Groups D and DI at , 0.01, and 0.001; &, &&, and &&&, the same between Groups CI and DI at , 0.01, and 0.001, respectively.
698435.fig.002a
(a)
698435.fig.002b
(b)
698435.fig.002c
(c)