Table 1: Differential diagnosis of erosions and blisters in the neonate and young .

Inherited or congenital disordersAcquired disorders

Epidermolysis bullosa hereditaria—all types (simplex, junctional, dystrophic)Immunobullous disorders
Ichthyosis bullosa of Siemens Epidermolysis bullosa acquisita
Netherton syndrome Linear IgA dermatosis
Congenital peeling skin syndromes Bullous pemphigoid
Pachyonychia congenita Cicatricial pemphigoid
Kindler’s syndrome Pemphigus
Congenital porphyriaInfectious diseases
Acrodermatitis enteropathica Herpes simplex
Incontinentia pigmenti Bullous impetigo
Ectodermal dysplasia Staphylococcal scalded skin syndrome
AEC syndrome (Hay-Wells syndrome) Congenital lues (pemphigus syphiliticus)
Ectodermal dysplasia with plakophilin 1 deficiency Other bacterial, viral or fungal infections
Congenital absence of skin (cutis aplasia)Other diseases or conditions
Congenital erosive dermatosis with reticulate supple scarring Bullous mastocytosis
Mendes da Costa syndrome Behcet disease
Shabbir’s syndrome (laryngo-onychocutaneous syndrome) Traumatic blisters (sucking, other)
Epidermolytic hyperkeratosis (bullous ichthyosiform erythroderma) Toxic epidermal necrolysis

by Eady et al. [2].