Review Article
Diagnostic Pitfalls in Newborns and Babies with Blisters and Erosions
Table 2
Variables causing problems in differential diagnosis.
| Clinical features | Similarity and overlapping of clinical features | Coexistance of different diseases | Colonization and/or superinfection | Absence of late changes in the neonate (scar formation, pigmentation changes, nail dystrophy) | Diagnostical methods | Sample (site of sample not representative, secondary alterations) | Timepoint of sample collection (i.e., higher herpes simplex virus load in early vesicles) | Sensitivity and specifity of method | Technical problems (wrong transportation media, ) | Experience in interpreting the results |
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