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Dermatology Research and Practice
Volume 2010, Article ID 214745, 5 pages
Review Article

The Influence of Pregnancy on the Recurrence of Cutaneous Malignant Melanoma in Women

1Department of Metabolic and Endocrine Diseases, Wilhelmina Children's Hospital, University Medical Centre Utrecht, 3584 EA Utrecht, The Netherlands
2Department of General Practice, University Medical Centre Utrecht, 3732 HJ De Bilt, The Netherlands
3Department of Surgical Oncology, VU University Medical Centre, 1081 HV Amsterdam, The Netherlands

Received 25 May 2010; Accepted 24 June 2010

Academic Editor: Ashfaq A. Marghoob

Copyright © 2010 M. Albersen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. The aim of this study was to determine whether pregnancy increases the recurrence risk of cutaneous malignant melanoma (CMM) in women with a history of stage I CMM. Methods. The electronic medical databases of Medline and Embase were explored. All 1084 obtained articles were screened on title and abstract using predetermined inclusion and exclusion criteria. A critical appraisal of relevance and validity was conducted on the remaining full text available articles. Results. Two studies were selected. Both studies revealed no significant difference in disease-free survival between women with stage I CMM and the control population. Conclusion. Pregnancy does not increase the recurrence risk of CMM in women with a history of stage I CMM.